Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.53 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.53 |
| ▸ | BCL2 | P10415 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | POLQ | O75417 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8202718 | 0.86 | PRKAB2 (0.55) | LTB4RLTB4R2SMN1; SMN2AKR1C3AKR1C2 | |
| SCHEMBL8069413 | 0.85 | SMN1; SMN2 (0.59) | LTB4RLTB4R2RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6701301 | 0.82 | SMN1; SMN2 (0.63) | LTB4RLTB4R2SMN1; SMN2AKR1C3AKR1C2 | |
| SCHEMBL31619636 | 0.82 | SMN1; SMN2 (0.51) | LTB4RLTB4R2RAB9ASMN1; SMN2AKR1C3 | |
| SCHEMBL18414391 | 0.80 | BCL2 (0.58) | LTB4RLTB4R2BCL2RAB9ASMN1; SMN2 | |
| SCHEMBL9288089 | 0.79 | CYP1A1 (0.50) | BCL2RAB9ASMN1; SMN2THRATHRB | |
| SCHEMBL7591657 | 0.78 | SMN1; SMN2 (0.75) | SMN1; SMN2AKR1C3AKR1C2KDM4EPOLB | |
| SCHEMBL4601656 | 0.77 | PLA2G2A (0.64) | RAB9ASMN1; SMN2KMT2AKDM4EPOLB | |
| SCHEMBL10909137 | 0.76 | PTPN1 (0.53) | LTB4R2BCL2RAB9ASMN1; SMN2 | |
| SCHEMBL20208770 | 0.76 | KDM4E (0.56) | SMN1; SMN2AKR1C3AKR1C2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379290-B1 | Flux composition | COOKSON GROUP PLC (GB) | 1993-10-27 | — | — | EP | claimed |