Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | CCNC | P24863 | 3/20 | 0.45 |
| ▸ | CDK8 | P49336 | 3/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19257561 | 0.88 | ERN1 (0.54) | MAOBTTRDPP4CCNCCDK8 | |
| SCHEMBL19257539 | 0.87 | JUN (0.49) | MAOBCCNCCDK8HSD17B1HSD17B2 | |
| SCHEMBL19257536 | 0.85 | HSD17B1 (0.47) | MAOBCCNCCDK8HSD17B1HSD17B2 | |
| SCHEMBL19257562 | 0.85 | MAOB (0.45) | MAOBTTRDPP4CCNCCDK8 | |
| SCHEMBL19257218 | 0.81 | CYP1A2 (0.49) | MAOBCCNCCDK8HSD17B1HSD17B2 | |
| SCHEMBL19257542 | 0.80 | CYP1A2 (0.44) | MAOBCCNCCDK8HSD17B1HSD17B2 | |
| SCHEMBL19257584 | 0.80 | HSD17B1 (0.48) | MAOBCCNCCDK8HSD17B1HSD17B2 | |
| SCHEMBL19257582 | 0.79 | CYP1A2 (0.44) | MAOBCCNCCDK8HSD17B1HSD17B2 | |
| SCHEMBL19257279 | 0.79 | HSD17B1 (0.47) | MAOBCCNCCDK8HSD17B1HSD17B2 | |
| SCHEMBL19257533 | 0.79 | CYP1A2 (0.47) | MAOBCCNCCDK8HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134146-A1 | GPBP INHIBITORS AND USES AND SCALEABLE SYNTHESIS THEREOF | FIBROSTATIN, S.L. (ES) | 2017-08-10 | — | — | WO | disclosed |