Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19257582 | 0.92 | CYP1A2 (0.44) | CYP1A2CYP3A4CYP2D6CYP2C9HSD17B1 | |
| SCHEMBL19257537 | 0.89 | CYP1A2 (0.46) | CYP1A2CYP3A4CYP2D6CYP2C9HSD17B1 | |
| SCHEMBL15602222 | 0.89 | ERN1 (0.46) | CYP1A2CYP3A4CYP2D6CYP2C9HSD17B1 | |
| SCHEMBL19257198 | 0.88 | JUN (0.44) | MAPTALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL19257539 | 0.86 | JUN (0.49) | CYP1A2CYP3A4CYP2D6CYP2C9HSD17B1 | |
| SCHEMBL19257725 | 0.85 | XDH (0.44) | CYP1A2CYP3A4CYP2D6CYP2C9HSD17B1 | |
| SCHEMBL19257538 | 0.83 | JUN (0.45) | MAPTALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL19257218 | 0.81 | CYP1A2 (0.49) | CYP1A2CYP3A4CYP2D6CYP2C9HSD17B1 | |
| SCHEMBL19257286 | 0.81 | HSD17B1 (0.42) | CYP1A2CYP3A4CYP2D6CYP2C9HSD17B1 | |
| SCHEMBL19257718 | 0.80 | MAOB (0.48) | CYP1A2CYP3A4CYP2D6CYP2C9HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134146-A1 | GPBP INHIBITORS AND USES AND SCALEABLE SYNTHESIS THEREOF | FIBROSTATIN, S.L. (ES) | 2017-08-10 | — | — | WO | disclosed |