Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22267911 | 1.00 | CCR3 (0.39) | CCR3PTPRBADRB2RAD52ADRB3 | |
| SCHEMBL22267912 | 0.86 | ADRB3 (0.39) | CCR3PTPRBADRB2RAD52ADRB3 | |
| SCHEMBL19257958 | 0.85 | PTPRB (0.47) | CCR3PTPRBADRB3CYP2C19LMNA | |
| SCHEMBL22267910 | 0.83 | CCR3 (0.36) | CCR3PTPRBADRB2RAD52ADRB3 | |
| SCHEMBL20586742 | 0.81 | CCR3 (0.47) | CCR3PTPRBRAD52ADRB3CYP2C19 | |
| SCHEMBL19209330 | 0.81 | CCR3 (0.47) | CCR3PTPRBRAD52ADRB3CYP2C19 | |
| SCHEMBL19257973 | 0.78 | RAD52 (0.46) | CCR3PTPRBADRB2RAD52CYP2C19 | |
| SCHEMBL8945778 | 0.77 | SLC6A2 (0.37) | CCR3PTPRBADRB3ALDH1A1SLC6A4 | |
| Hydrochloric Acid SCHEMBL20586638 | 0.77 | RAD52 (0.45) | CCR3PTPRBADRB2RAD52CYP2C19 | |
| Hydrochloric Acid SCHEMBL19209193 | 0.77 | RAD52 (0.45) | CCR3PTPRBADRB2RAD52CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134547-A1 | TUBULYSIN ANALOGS AND METHODS FOR THEIR PREPARATION | PFIZER INC. (US) | 2017-08-10 | — | — | WO | disclosed |