Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 14/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19684530 | 0.63 | NTRK1 (0.40) | NTRK1 | |
| SCHEMBL14236197 | 0.60 | IRAK4 (0.44) | NTRK1TLR9TLR8TLR7 | |
| SCHEMBL19259010 | 0.59 | GABBR2 (0.53) | — | |
| SCHEMBL13041959 | 0.56 | NTRK1 (0.37) | NTRK1TLR9TLR8TLR7 | |
| SCHEMBL11922157 | 0.56 | NTRK1 (0.37) | NTRK1 | |
| SCHEMBL13616224 | 0.55 | BRD4 (0.42) | NTRK1TLR9TLR8TLR7 | |
| SCHEMBL30968079 | 0.55 | NTRK1 (0.36) | NTRK1TLR9TLR8TLR7 | |
| SCHEMBL27975444 | 0.55 | LRRK2 (0.42) | NTRK1TLR9TLR8TLR7 | |
| SCHEMBL16091256 | 0.55 | NTRK1 (0.36) | NTRK1TLR9TLR8TLR7 | |
| SCHEMBL19325285 | 0.54 | TLR9 (0.37) | NTRK1TLR9TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133669-A1 | 5, 7-DIAZAINDOLE AND 5, 7-DIAZAINDAZOLE DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |