SCHEMBL12759482

SCHEMBL12759482

Cc1cccc(C)c1-c1cnc2c3ccccc3c3ccccc3n12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 1/20 0.39
FTO Q9C0B1 1/20 0.39
POLB P06746 3/20 0.35
MAPT P10636 4/20 0.33
HPGD P15428 3/20 0.33
LMNA P02545 3/20 0.33
MEN1 O00255 2/20 0.33
GAA P10253 2/20 0.33
KMT2A Q03164 2/20 0.33
PTGER4 P35408 2/20 0.33
NTRK1 P04629 1/20 0.33
HTT P42858 1/20 0.33
WEE1 P30291 1/20 0.33
HSD17B10 Q99714 4/20 0.33
ALDH1A1 P00352 4/20 0.33
KDM4E B2RXH2 3/20 0.33
RAB9A P51151 2/20 0.33
NPC1 O15118 1/20 0.33
CHEK1 O14757 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19595218 0.90 NPC1 (0.37) ALKBH5FTOPOLBMAPTHPGD
SCHEMBL19258032 0.88 ALKBH5 (0.37) ALKBH5FTOPOLBMAPTHPGD
SCHEMBL21917735 0.88 PTGER4 (0.35) ALKBH5FTOPOLBMAPTHPGD
SCHEMBL29631725 0.88 PGR (0.38) POLBMAPTLMNAMEN1KMT2A
SCHEMBL841646 0.88 PGR (0.38) POLBMAPTLMNAMEN1KMT2A
SCHEMBL840110 0.87 WEE1 (0.32) ALKBH5FTOMAPTHPGDMEN1
SCHEMBL12077046 0.87 BAZ2B (0.34) ALKBH5FTOPOLBMAPTHPGD
SCHEMBL29807954 0.87 BAZ2B (0.34) ALKBH5FTOPOLBMAPTHPGD
SCHEMBL29801927 0.86 PGR (0.37) MAPTLMNAMEN1KMT2AWEE1
SCHEMBL29911566 0.86 PGR (0.37) MAPTLMNAMEN1KMT2AWEE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-20150311455-A1 Method Of Forming Metal Complex Compound, And Organic Electroluminescence Device UDC IRELAND LTD (IE) 2015-10-29 US disclosed
US-20150311455-A1 Method Of Forming Metal Complex Compound, And Organic Electroluminescence Device UDC IRELAND LTD (IE) 2015-10-29 US disclosed
US-9062084-B2 Method of forming metal complex compound, and organic electroluminescence device UDC Ireland (IE) 2015-06-23 US disclosed
US-9062084-B2 Method of forming metal complex compound, and organic electroluminescence device UDC Ireland (IE) 2015-06-23 US disclosed
US-20110050093-A1 METHOD OF FORMING METAL COMPLEX COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
US-20110050093-A1 METHOD OF FORMING METAL COMPLEX COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OXGR1, OCIAD1 ALKBH5 2293/4885FTO 435/4885POLB 3665/4885
US-20110050093-A1 METHOD OF FORMING METAL COMPLEX COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE ZFR, PORCN, OR10J3 ALKBH5 1584/4885FTO 1019/4885POLB 1381/4885
US-20150311455-A1 Method Of Forming Metal Complex Compound, And Organic Electroluminescence Device ZFR, PORCN, OR10J3 ALKBH5 1584/4885FTO 1019/4885POLB 1381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.