Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA3 | P07451 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19646046 | 0.97 | — | — | |
| SCHEMBL11718481 | 0.90 | — | — | |
| SCHEMBL10883735 | 0.87 | TRPV1 (0.33) | LMNATRPV1TRPA1 | |
| SCHEMBL27517780 | 0.84 | LMNA (0.33) | LMNA | |
| SCHEMBL7947746 | 0.80 | OPRM1 (0.50) | ALDH1A1TRPV1TRPA1 | |
| SCHEMBL403601 | 0.78 | — | — | |
| SCHEMBL8953948 | 0.78 | DNM1 (0.38) | DNM1CA12CA1CA2CA3 | |
| SCHEMBL15466755 | 0.78 | DNM1 (0.38) | DNM1CA12CA1CA2CA3 | |
| SCHEMBL27510526 | 0.78 | LMNA (0.33) | LMNA | |
| SCHEMBL6577127 | 0.77 | DNM1 (0.42) | DNM1CA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732341-B2 | Methods of delivering multiple targeting oligonucleotides to a cell using cleavable linkers | TRANSLATE BIO MA, INC. (US) | 2017-08-15 | — | — | US | disclosed |