Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 12/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 12/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19258476 | 0.81 | GRIN1 (0.33) | GRIN1GRIN2B | |
| SCHEMBL19259114 | 0.77 | NPC1 (0.34) | GRIN1GRIN2B | |
| SCHEMBL33527364 | 0.73 | GRIN1 (0.36) | GRIN1GRIN2B | |
| SCHEMBL2361171 | 0.72 | GRIN1 (0.45) | GRIN1GRIN2B | |
| SCHEMBL19258951 | 0.67 | GRIN2B (0.33) | GRIN1GRIN2B | |
| SCHEMBL19258560 | 0.65 | GRIN1 (0.34) | GRIN1GRIN2BCYP11B2 | |
| SCHEMBL10124275 | 0.65 | NR3C1 (0.49) | — | |
| SCHEMBL16035395 | 0.65 | CLK1 (0.31) | — | |
| SCHEMBL14299254 | 0.62 | NR3C1 (0.44) | — | |
| SCHEMBL19630106 | 0.60 | PIK3CB (0.41) | GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133657-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |