Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | PKLR | P30613 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22960089 | 0.93 | L3MBTL1 (0.48) | LMNAL3MBTL1ATMCYP2A6TDP1 | |
| SCHEMBL758323 | 0.81 | ATM (0.66) | LMNAL3MBTL1ATMF2PRSS1 | |
| SCHEMBL25932918 | 0.78 | CYP2A6 (0.62) | LMNACYP2A6TDP1PKMCYP1A2 | |
| SCHEMBL8243698 | 0.78 | LMNA (0.59) | LMNAL3MBTL1ATMTDP1F2 | |
| SCHEMBL2611773 | 0.78 | LMNA (0.59) | LMNAL3MBTL1ATMTDP1F2 | |
| SCHEMBL29800886 | 0.78 | LMNA (0.59) | LMNAL3MBTL1ATMTDP1F2 | |
| SCHEMBL2286348 | 0.78 | LMNA (0.59) | LMNAL3MBTL1ATMTDP1F2 | |
| SCHEMBL18782754 | 0.78 | CA1 (0.44) | LMNAL3MBTL1ATMCYP2A6TDP1 | |
| SCHEMBL21830632 | 0.76 | L3MBTL1 (0.34) | LMNAL3MBTL1ATM | |
| SCHEMBL20381934 | 0.76 | CYP2A6 (0.50) | LMNAL3MBTL1CYP2A6PKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136466-A1 | HEME PROTEIN CATALYSTS FOR CARBON-SILICON BOND FORMATION IN VITRO AND IN VIVO | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2017-08-10 | — | — | WO | disclosed |