Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 16/20 | 0.52 |
| ▸ | CA2 | P00918 | 16/20 | 0.52 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19259536 | 0.77 | KDM4E (0.57) | CA1CA2 | |
| SCHEMBL20610218 | 0.74 | CA1 (0.45) | CA1CA2PTGES2CA9CA12 | |
| SCHEMBL12363458 | 0.70 | TUBB4A (0.37) | — | |
| SCHEMBL15881155 | 0.69 | ALDH1A1 (0.43) | KIF11 | |
| SCHEMBL27524586 | 0.69 | CA1 (0.48) | CA1CA2CA9CA12CA4 | |
| SCHEMBL1645328 | 0.68 | CA1 (1.00) | CA1CA2CA9CA12ACHE | |
| SCHEMBL19259541 | 0.67 | APLNR (0.45) | CA1CA2PTGES2CA9CA12 | |
| SCHEMBL1645211 | 0.67 | CA1 (0.62) | CA1CA2 | |
| SCHEMBL19126834 | 0.67 | SMN1; SMN2 (0.47) | CA1CA2CA9CA12CA4 | |
| SCHEMBL15880582 | 0.67 | KMT2A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3416948-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | The University Of Queensland (AU) | 2018-12-26 | — | — | EP | disclosed |
| WO-2017140778-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | THE UNIVERSITY OF QUEENSLAND (AU) | 2017-08-24 | — | — | WO | disclosed |