SCHEMBL1925970

SCHEMBL1925970

CC(O)C(=O)OC(=O)/C=C/c1ccccc1.[KH]

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.51
ALDH1A1 P00352 2/20 0.51
AKR1B10 O60218 3/20 0.49
AKR1B1 P15121 3/20 0.49
TDP1 Q9NUW8 2/20 0.49
GLA P06280 1/20 0.49
KMT2A Q03164 3/20 0.48
MEN1 O00255 1/20 0.48
MAPT P10636 3/20 0.47
HDAC3 O15379 2/20 0.47
HDAC4 P56524 2/20 0.47
HDAC1 Q13547 2/20 0.47
HDAC2 Q92769 2/20 0.47
HDAC8 Q9BY41 2/20 0.47
HDAC6 Q9UBN7 2/20 0.47
TNKS O95271 1/20 0.47
HCAR2 Q8TDS4 1/20 0.47
HDAC7 Q8WUI4 1/20 0.47
HDAC10 Q969S8 1/20 0.47
HDAC11 Q96DB2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7804575 0.98 LMNA (0.53) LMNAALDH1A1AKR1B10AKR1B1TDP1
SCHEMBL29002904 0.87 LMNA (0.54) LMNAALDH1A1AKR1B10AKR1B1TDP1
SCHEMBL30013490 0.84 CA12 (0.64) AKR1B10AKR1B1HCAR2CYP2D6CYP2C9
SCHEMBL29084174 0.83 LMNA (0.54) LMNAALDH1A1AKR1B10AKR1B1TDP1
SCHEMBL28905351 0.81 LMNA (0.51) LMNAALDH1A1AKR1B10AKR1B1TDP1
SCHEMBL9247555 0.80 MAPT (0.64) LMNAALDH1A1AKR1B10AKR1B1TDP1
SCHEMBL21803794 0.80 MAPT (0.64) LMNAALDH1A1AKR1B10AKR1B1TDP1
SCHEMBL775716 0.80 MAPT (0.64) LMNAALDH1A1AKR1B10AKR1B1TDP1
SCHEMBL15569162 0.78 LMNA (0.53) LMNAALDH1A1AKR1B10AKR1B1KMT2A
SCHEMBL29010371 0.78 LMNA (0.56) LMNAALDH1A1AKR1B10AKR1B1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9695102-B2 Alkali metal cinnamate powder and method for preparation PURAC BIOCHEM BV (NL) 2017-07-04 US disclosed
EP-2330094-B1 Alkali metal cinnamate powder and method for preparation PURAC BIOCHEM BV (NL) 2017-02-08 EP disclosed
US-20120282468-A1 ALKALI METAL CINNAMATE POWDER AND METHOD FOR PREPARATION PURAC BIOCHEM BV (NL) 2012-11-08 US disclosed
CN-102666465-A Alkali metal cinnamate powder and method for preparation PURAC BIOCHEM BV 2012-09-12 CN disclosed
WO-2011067330-A1 ALKALI METAL CINNAMATE POWDER AND METHOD FOR PREPARATION PURAC BIOCHEM BV (NL) 2011-06-09 WO disclosed
EP-2330094-A1 Alkali metal cinnamate powder and method for preparation PURAC Biochem BV (NL) 2011-06-08 EP disclosed