Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15569161 | 0.90 | LMNA (0.51) | LMNAAKR1B10AKR1B1ALDH1A1CA12 | |
| SCHEMBL30013897 | 0.88 | PYGL (0.56) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL3632717 | 0.82 | TTR (0.57) | LMNAAKR1B10AKR1B1ALDH1A1CA12 | |
| SCHEMBL29084174 | 0.81 | LMNA (0.54) | LMNAAKR1B10AKR1B1ALDH1A1CA12 | |
| SCHEMBL5081389 | 0.80 | SMN1; SMN2 (0.46) | LMNAMAPTHCAR2SMN1; SMN2 | |
| Styrene SCHEMBL4403563 | 0.80 | ALDH1A1 (0.47) | LMNACASP1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7804575 | 0.80 | LMNA (0.53) | LMNAAKR1B10AKR1B1ALDH1A1CA12 | |
| SCHEMBL28905351 | 0.78 | LMNA (0.51) | LMNAAKR1B10AKR1B1ALDH1A1CA12 | |
| SCHEMBL1925970 | 0.78 | LMNA (0.51) | LMNAAKR1B10AKR1B1ALDH1A1CA12 | |
| SCHEMBL21803794 | 0.78 | MAPT (0.64) | LMNAAKR1B10AKR1B1ALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2885411-B1 | MEANS AND METHODS FOR ALTERING THE LIGNIN PATHWAY IN PLANTS | VIB VZW (BE) | 2018-12-05 | — | — | EP | disclosed |
| US-10006041-B2 | Means and methods for altering the lignin pathway in plants | VIB VZW (BE) | 2018-06-26 | — | — | US | disclosed |
| US-20150232872-A1 | MEANS AND METHODS FOR ALTERING THE LIGNIN PATHWAY IN PLANTS | UNIVERSITEIT GENT (BE) | 2015-08-20 | — | — | US | disclosed |
| EP-2885411-A1 | MEANS AND METHODS FOR ALTERING THE LIGNIN PATHWAY IN PLANTS | VIB vzw (BE) | 2015-06-24 | — | — | EP | disclosed |
| WO-2014027021-A1 | MEANS AND METHODS FOR ALTERING THE LIGNIN PATHWAY IN PLANTS | VIB VZW (BE) | 2014-02-20 | — | — | WO | disclosed |