SCHEMBL19259821

SCHEMBL19259821

CS(=O)(=O)c1cc(-c2ccccc2)cc(S(=O)(=O)c2ccc(CN)s2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LOX P28300 14/20 1.00
LOXL2 Q9Y4K0 9/20 1.00
KCNH2 Q12809 2/20 1.00
AOC3 Q16853 2/20 1.00
LOXL3 P58215 1/20 1.00
MAOB P27338 1/20 0.80
MAOA P21397 1/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30846484 0.99 LOX (0.97) LOXLOXL2KCNH2AOC3LOXL3
SCHEMBL19259977 0.89 LOX (1.00) LOXLOXL2KCNH2AOC3LOXL3
SCHEMBL19274591 0.88 LOX (1.00) LOXLOXL2KCNH2AOC3LOXL3
SCHEMBL19259962 0.88 LOX (1.00) LOXLOXL2KCNH2AOC3LOXL3
SCHEMBL20983542 0.87 LOX (1.00) LOXLOXL2KCNH2AOC3LOXL3
Hydrochloric Acid SCHEMBL19259609 0.86 LOX (0.98) LOXLOXL2KCNH2AOC3LOXL3
SCHEMBL19274554 0.86 LOX (1.00) LOXLOXL2KCNH2AOC3LOXL3
SCHEMBL19274713 0.85 LOX (1.00) LOXLOXL2KCNH2AOC3LOXL3
SCHEMBL29970885 0.85 LOX (1.00) LOXLOXL2KCNH2AOC3LOXL3
SCHEMBL19274855 0.85 LOXL2 (1.00) LOXLOXL2KCNH2AOC3LOXL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116531367-B Application of CCT365623 in preparation of medicine for treating parkinsonism 中南大学湘雅医院 2024-04-19 CN claimed
EP-4314018-A1 METHODS AND COMPOSITIONS FOR HIGH-POTENCY POLYPEPTIDE-BASED PROTEIN INHIBITION Baylor College of Medicine (US) 2024-02-07 EP claimed
US-20230355711-A1 VIMENTIN AND FRAGMENTS OR DERIVATIVES THEREOF FOR CORONAVIRUS TREATMENT AND PREVENTION THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS 2023-11-09 US claimed
CN-116531367-A Application of CCT365623 in preparation of medicines for treating parkinsonism 中南大学湘雅医院 2023-08-04 CN claimed
US-20230210902-A1 SARS-COV-2-SPECIFIC T CELLS NATIONAL INSTITUTES OF HEALTH 2023-07-06 US claimed
EP-4149496-A1 SARS-COV-2-SPECIFIC T CELLS Board of Regents, The University of Texas System (US) 2023-03-22 EP claimed
US-20220401553-A1 PARAPOXVIRUS FOR CONDITIONING FOR AND TREATMENT OF CORONAVIRUS INFECTIONS AICURIS GMBH & CO. KG (DE) 2022-12-22 US claimed
WO-2022213076-A1 METHODS AND COMPOSITIONS FOR HIGH-POTENCY POLYPEPTIDE-BASED PROTEIN INHIBITION BAYLOR COLLEGE OF MEDICINE (US) 2022-10-06 WO claimed
EP-3906970-B1 PARAPOXVIRUS FOR CONDITIONING AND TREATMENT OF CORONAVIRUS INFECTIONS AICURIS GMBH & CO KG (DE) 2022-07-06 EP claimed
US-20220193204-A1 USES OF A2 DOMAIN OF VON WILLEBRAND FACTOR BAYLOR COLLEGE OF MEDICINE (US) 2022-06-23 US claimed
EP-3969036-A1 USES OF A2 DOMAIN OF VON WILLEBRAND FACTOR Baylor College of Medicine (US) 2022-03-23 EP claimed
EP-4714452-A1 METHODS FOR TREATING SARS COV-2 INFECTIONS Gilead Sciences, Inc. (US) 2026-03-25 EP disclosed
EP-4642465-A1 A CANCER ASSOCIATED FIBROBLAST (CAF) INHIBITOR FOR USE WITH AN ALTERNATING ELECTRIC FIELD IN A METHOD OF TREATING DISEASES SUCH AS CANCER Novocure GmbH (CH) 2025-11-05 EP disclosed
EP-4581011-A1 NOVEL SELECTIVE INHIBITORS OF LYSYL OXIDASES Syntara Limited (AU) 2025-07-09 EP disclosed
CN-119968356-A Novel lysyl oxidase selective inhibitors 辛塔拉有限公司 2025-05-09 CN disclosed
US-20190152966-A1 Methylamine Derivatives as Lysysl Oxidase Inhibitors for the Treatment of Cancer THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2019-05-23 US disclosed
US-20190152966-A1 Methylamine Derivatives as Lysysl Oxidase Inhibitors for the Treatment of Cancer THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2019-05-23 US disclosed
EP-3416956-A1 METHYLAMINE DERIVATIVES AS LYSYSL OXIDASE INHIBITORS FOR THE TREATMENT OF CANCER The Institute of Cancer Research : The Royal Cancer Hospital (GB) 2018-12-26 EP disclosed
WO-2017141049-A1 METHYLAMINE DERIVATIVES AS LYSYSL OXIDASE INHIBITORS FOR THE TREATMENT OF CANCER THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2017-08-24 WO disclosed
WO-2017141049-A1 METHYLAMINE DERIVATIVES AS LYSYSL OXIDASE INHIBITORS FOR THE TREATMENT OF CANCER THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2017-08-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190152966-A1 Methylamine Derivatives as Lysysl Oxidase Inhibitors for the Treatment of Cancer LOXL1, LOXL3, LOXL2 LOX 4/4885LOXL2 3/4885KCNH2 4429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.