Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCD1 | P51178 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 4/20 | 0.44 |
| ▸ | FGF1 | P05230 | 1/20 | 0.40 |
| ▸ | FGF2 | P09038 | 1/20 | 0.40 |
| ▸ | VEGFA | P15692 | 1/20 | 0.40 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.40 |
| ▸ | HLCS | P50747 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21909 | 0.99 | PLCD1 (0.48) | PLCD1F2FGF1FGF2VEGFA | |
| SCHEMBL5685965 | 0.96 | F2 (0.47) | PLCD1F2HLCS | |
| SCHEMBL7532610 | 0.91 | PLCD1 (0.48) | PLCD1F2FGF1FGF2VEGFA | |
| SCHEMBL7644975 | 0.91 | PLCD1 (0.43) | PLCD1F2FGF1FGF2VEGFA | |
| SCHEMBL29426309 | 0.88 | PLCD1 (0.49) | PLCD1F2FGF1FGF2VEGFA | |
| SCHEMBL20129499 | 0.87 | PLCD1 (0.49) | PLCD1F2FGF1FGF2VEGFA | |
| SCHEMBL29627228 | 0.87 | PLCD1 (0.47) | PLCD1F2FGF1FGF2VEGFA | |
| SCHEMBL9004512 | 0.86 | F2 (0.43) | PLCD1F2FGF1FGF2VEGFA | |
| Biotin SCHEMBL9489122 | 0.85 | F2 (0.48) | F2HLCSTDP1 | |
| SCHEMBL6534840 | 0.84 | TK1 (0.46) | F2FGF1FGF2VEGFAHPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927699-B2 | Methods for obtaining thermostable enzymes, DNA polymerase I variants from Thermus aquaticus having new catalytic activities, methods for obtaining the same, and applications to the same | INSTITUT PASTEUR (FR) | 2015-01-06 | — | — | US | disclosed |
| EP-2607378-A2 | Methods for obtaining thermostable enzymes, DNA polymerase I variants from thermus aquaticus having new catalytic activities, methods for obtaining the same, and applications of the same | INSTITUT PASTEUR (FR) | 2013-06-26 | — | — | EP | disclosed |
| EP-1718740-B1 | METHODS FOR OBTAINING THERMOSTABLE ENZYMES, DNA POLYMERASE I VARIANTS FROM THERMUS AQUATICUS HAVING NEW CATALYTIC ACTIVITIES, METHODS FOR OBTAINING THE SAME, AND APPLICATIONS TO THE SAME | PASTEUR INSTITUT (FR) | 2013-05-22 | — | — | EP | disclosed |
| EP-2330119-A2 | Methods for obtaining thermostable enzymes, DNA polymerase I variants from thermus aquaticus having new catalytic activities, methods for obtaining the same, and applications of the same | INSTITUT PASTEUR (FR) | 2011-06-08 | — | — | EP | disclosed |
| US-7488816-B2 | Nucleotide sequences coding heat resistant polypeptide for use in enhancing nucleic acid amplification | INSTITUT PASTEUR (FR) | 2009-02-10 | — | — | US | disclosed |
| US-7417133-B2 | Nucleotide sequences coding heat resistant polypeptide for use in enhancing nucleic acid amplification | INSTITUT PASTEUR (FR) | 2008-08-26 | — | — | US | disclosed |
| US-20080014609-A1 | Methods for Obtaining Thermostable Enzymes, Dna Polymerase I Variants from Thermus Aquaticus Having New Catalytic Activities, Methods for Obtaining the Same, and Applications to the Same | INSTITUT PASTEUR (FR) | 2008-01-17 | — | — | US | disclosed |
| EP-1718740-A2 | METHODS FOR OBTAINING THERMOSTABLE ENZYMES, DNA POLYMERASE I VARIANTS FROM THERMUS AQUATICUS HAVING NEW CATALYTIC ACTIVITIES, METHODS FOR OBTAINING THE SAME, AND APPLICATIONS TO THE SAME | INSTITUT PASTEUR (FR) | 2006-11-08 | — | — | EP | disclosed |
| US-20050250131-A1 | Nucleotide sequences coding heat resistant polypeptide for use in enhancing nucleic acid amplification | INSTITUT PASTEUR (FR) | 2005-11-10 | — | — | US | disclosed |
| WO-2005083068-A2 | METHODS FOR OBTAINING THERMOSTABLE ENZYMES, DNA POLYMERASE I VARIANTS FROM THERMUS AQUATICUS HAVING NEW CATALYTIC ACTIVITIES, METHODS FOR OBTAINING THE SAME, AND APPLICATIONS TO THE SAME | INSTITUT PASTEUR (FR) | 2005-09-09 | — | — | WO | disclosed |
| US-20050191635-A1 | Nucleotide sequences coding heat resistant polypeptide for use in enhancing nucleic acid amplification | INSTITUT PASTEUR (FR) | 2005-09-01 | — | — | US | disclosed |