SCHEMBL20129499

SCHEMBL20129499

O=C(CCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21)NC/C=C/c1cn([C@H]2C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]c1=O

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PLCD1 P51178 1/20 0.49
F2 P00734 2/20 0.45
TYMS P04818 1/20 0.43
FGF1 P05230 1/20 0.43
FGF2 P09038 1/20 0.43
VEGFA P15692 1/20 0.43
HPSE Q9Y251 1/20 0.43
HLCS P50747 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
PRSS1 P07477 1/20 0.39
PRSS2 P07478 1/20 0.39
PRSS3 P35030 1/20 0.39
TPSAB1 Q15661 1/20 0.39
ITGB1 P05556 1/20 0.39
ITGA4 P13612 1/20 0.39
CNR1 P21554 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29426309 0.99 PLCD1 (0.49) PLCD1F2TYMSFGF1FGF2
SCHEMBL29627228 0.98 PLCD1 (0.47) PLCD1F2TYMSFGF1FGF2
SCHEMBL14399749 0.92 PLCD1 (0.47) PLCD1F2FGF1FGF2VEGFA
SCHEMBL9979889 0.92 PLCD1 (0.48) PLCD1F2FGF1FGF2VEGFA
SCHEMBL12994951 0.92 PLCD1 (0.48) PLCD1F2FGF1FGF2VEGFA
SCHEMBL14406729 0.92 PLCD1 (0.48) PLCD1F2FGF1FGF2VEGFA
SCHEMBL28312091 0.91 TYMS (0.52) PLCD1F2TYMS
SCHEMBL20126981 0.90 PLCD1 (0.48) PLCD1F2FGF1FGF2VEGFA
SCHEMBL14370813 0.88 PLCD1 (0.46) PLCD1F2FGF1FGF2VEGFA
SCHEMBL21909 0.88 PLCD1 (0.48) PLCD1F2FGF1FGF2VEGFA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111518873-B Optimized method for amplifying target nucleic acid and application 上海羿鸣生物科技有限公司 2024-07-09 CN claimed
CN-115820595-A Optimized polymerase for amplifying target nucleic acid, composite system and application 南京君华基因科技有限公司 2023-03-21 CN claimed
WO-2022232087-A1 METHODS FOR PERFORMING IN VITRO TRANSCRIPTION USING dUTP NUTCRACKER THERAPEUTICS, INC. (US) 2022-11-03 WO claimed
CN-111454926-B Optimized polymerase for amplifying target nucleic acid, composite system and application 南京君华基因科技有限公司 2022-10-28 CN claimed
CN-115058469-A Method for labeling 3' -end biotin of short DNA fragment 深圳大学 2022-09-16 CN claimed
EP-4716752-A2 ENDONUCLEASE SYSTEMS Metagenomi, Inc. (US) 2026-04-01 EP disclosed
US-12584169-B2 Compositions and methods for improving sample identification in indexed nucleic acid libraries ILLUMINA, INC. (US) 2026-03-24 US disclosed
EP-4709863-A2 SYSTEMS AND METHODS FOR TRANSPOSING CARGO NUCLEOTIDE SEQUENCES Metagenomi, Inc. (US) 2026-03-18 EP disclosed
EP-4705464-A2 BASE EDITING ENZYMES Metagenomi, Inc. (US) 2026-03-11 EP disclosed
WO-2026044118-A1 ENDONUCLEASE SYSTEMS METAGENOMI, INC. (US) 2026-02-26 WO disclosed
EP-4684009-A1 IMPROVED METHODS AND COMPOSITIONS FOR CRISPR INTERFERENCE AND ACTIVATION Algen Biotechnologies, Inc. (US) 2026-01-28 EP disclosed
EP-4677092-A2 CLASS 2, TYPE V CRISPR SYSTEMS Metagenomi, Inc. (US) 2026-01-14 EP disclosed
WO-2022056324-A1 BASE EDITING ENZYMES METAGENOMI IP TECHNOLOGIES, LLC (US) 2022-03-17 WO disclosed
WO-2022056301-A1 BASE EDITING ENZYMES METAGENOMI IP TECHNOLOGIES, LLC (US) 2022-03-17 WO disclosed
WO-2022046662-A1 SYSTEMS AND METHODS FOR TRANSPOSING CARGO NUCLEOTIDE SEQUENCES METAGENOMI IP TECHNOLOGIES, LLC (US) 2022-03-03 WO disclosed
US-20220065849-A1 IDENTIFICATION OF COGNATE PAIRS OF LIGANDS AND RECEPTORS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2022-03-03 US disclosed
US-20210180118-A1 METHODS OF NUCLEIC ACID SAMPLE PREPARATION FOR IMMUNE REPERTOIRE SEQUENCING ARCHERDX, LLC (US) 2021-06-17 US disclosed
US-20210054435-A1 METHODS OF NUCLEIC ACID SAMPLE PREPARATION ArcherDX, Inc. (US) 2021-02-25 US disclosed
US-20180155767-A1 METHODS OF NUCLEIC ACID SAMPLE PREPARATION FOR IMMUNE REPERTOIRE SEQUENCING ArcherDX, Inc. (US) 2018-06-07 US disclosed
US-20180127806-A1 METHODS OF NUCLEIC ACID SAMPLE PREPARATION ArcherDX, Inc. (US) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180155767-A1 METHODS OF NUCLEIC ACID SAMPLE PREPARATION FOR IMMUNE REPERTOIRE SEQUENCING TLR9, HAVCR2, IGSF11 PLCD1 2982/4885F2 3361/4885TYMS 755/4885
US-12584169-B2 Compositions and methods for improving sample identification in indexed nucleic acid libraries DCLRE1B, RNGTT, FEN1 PLCD1 1925/4885F2 3840/4885TYMS 391/4885
US-20210180118-A1 METHODS OF NUCLEIC ACID SAMPLE PREPARATION FOR IMMUNE REPERTOIRE SEQUENCING TLR9, HAVCR2, IGSF11 PLCD1 2982/4885F2 3361/4885TYMS 755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.