Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.30 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17399521 | 1.00 | ALDH1A1 (0.33) | ALDH1A1CYP2D6ALOX15EP300KAT2B | |
| SCHEMBL12572575 | 0.79 | ALDH1A1 (0.47) | ALDH1A1CYP2D6ALOX15 | |
| SCHEMBL18868445 | 0.79 | ALDH1A1 (0.47) | ALDH1A1CYP2D6ALOX15 | |
| SCHEMBL17703871 | 0.78 | ALDH1A1 (0.38) | ALDH1A1CYP2D6ALOX15FFAR1MAPT | |
| SCHEMBL13819787 | 0.78 | ALDH1A1 (0.50) | ALDH1A1ALOX15FFAR1MAPTCYP19A1 | |
| SCHEMBL15223579 | 0.78 | ALDH1A1 (0.50) | ALDH1A1ALOX15FFAR1MAPTCYP19A1 | |
| SCHEMBL17676487 | 0.78 | ALDH1A1 (0.50) | ALDH1A1ALOX15FFAR1MAPTCYP19A1 | |
| SCHEMBL17399089 | 0.76 | ALDH1A1 (0.33) | ALDH1A1PPARG | |
| SCHEMBL17460947 | 0.76 | LMNA (0.41) | ALDH1A1MAPTOXER1 | |
| SCHEMBL19261401 | 0.76 | ALDH1A1 (0.33) | ALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9738631-B2 | Compositions and methods for the treatment of neurological disorders | CELLIX BIO PRIVATE LIMITED (IN) | 2017-08-22 | — | — | US | disclosed |