Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SPR | P35270 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.37 |
| ▸ | PDE5A | O76074 | 6/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14488354 | 0.83 | GRIN1 (0.37) | GRIN1GRIN2BPDE5A | |
| SCHEMBL19264147 | 0.81 | SPR (0.38) | L3MBTL1SPRGRIN1GRIN2BPDE5A | |
| SCHEMBL14488524 | 0.80 | PDE5A (0.36) | GRIN1GRIN2BPDE5A | |
| SCHEMBL19264334 | 0.79 | PDE5A (0.54) | L3MBTL1PDE5ACYP1A2USP2CYP3A4 | |
| SCHEMBL19264146 | 0.79 | L3MBTL1 (0.46) | L3MBTL1SPRGRIN1GRIN2BPDE5A | |
| SCHEMBL15937438 | 0.78 | GRIN1 (0.34) | GRIN1GRIN2BPDE5A | |
| SCHEMBL19264469 | 0.78 | GRIN1 (0.36) | GRIN1GRIN2BPDE5A | |
| SCHEMBL19264504 | 0.78 | PDE5A (0.35) | GRIN1GRIN2BPDE5A | |
| SCHEMBL25975747 | 0.77 | KMT2A (0.46) | L3MBTL1SPRPDE5A | |
| SCHEMBL19264503 | 0.76 | PTGDR2 (0.41) | L3MBTL1SPRGRIN1GRIN2BPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2729476-B1 | HETEROARYL SUBSTITUTED PYRAZOLOPYRIDINES AND THEIR USE AS STIMULATORS OF SOLUBLE GUANYLATE CYCLASE | BAYER IP GMBH (DE) | 2017-08-23 | — | — | EP | disclosed |