Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GRK6 | P43250 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19265503 | 0.86 | LRRK2 (0.36) | — | |
| SCHEMBL19265523 | 0.84 | TLR8 (0.35) | PKMHSD17B10LMNATSHRHPGD | |
| SCHEMBL19265705 | 0.84 | FDFT1 (0.38) | HSD17B10LMNAHPGDRAB9AMAPT | |
| SCHEMBL19265526 | 0.84 | TLR8 (0.40) | HSD17B10HPGDNPC1RAB9AMAPT | |
| SCHEMBL19265638 | 0.84 | KDM4E (0.36) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL19265449 | 0.83 | TLR8 (0.41) | HSD17B10LMNATSHRHPGDKMT2A | |
| SCHEMBL19265644 | 0.82 | MMP2 (0.41) | HSD17B10HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL19265546 | 0.81 | TLR8 (0.33) | HSD17B10HPGDNPC1RAB9AMAPT | |
| SCHEMBL19265650 | 0.78 | KDM4E (0.39) | HSD17B10HPGDNPC1RAB9ACHEK1 | |
| SCHEMBL19265672 | 0.77 | CMA1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3208263-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | VentiRx Pharmaceuticals, Inc. (US) | 2017-08-23 | — | — | EP | disclosed |