Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MASP2 | O00187 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 1/20 | 0.35 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19265523 | 0.93 | TLR8 (0.35) | LMNAKDM4EHPGDMEN1KMT2A | |
| SCHEMBL19265546 | 0.93 | TLR8 (0.33) | FDFT1STSCYP1A2CYP3A4RAB9A | |
| SCHEMBL19265638 | 0.92 | KDM4E (0.36) | KDM4EPOLBALDH1A1CA1CA2 | |
| SCHEMBL19265526 | 0.92 | TLR8 (0.40) | CYP1A2RAB9AKDM4EHPGDMEN1 | |
| SCHEMBL19265644 | 0.90 | MMP2 (0.41) | HPGDALDH1A1HSD17B10SMN1; SMN2TLR8 | |
| SCHEMBL19265449 | 0.89 | TLR8 (0.41) | LMNAKDM4EHPGDMEN1KMT2A | |
| SCHEMBL19265650 | 0.86 | KDM4E (0.39) | CYP1A2CYP3A4RAB9AKDM4EHPGD | |
| SCHEMBL18771933 | 0.85 | TLR8 (0.34) | STSCYP1A2CYP3A4RAB9AKDM4E | |
| SCHEMBL18772002 | 0.84 | HPGD (0.37) | LMNARAB9AHPGDMEN1POLB | |
| SCHEMBL19265647 | 0.84 | PRKCZ (0.37) | MEN1KMT2AL3MBTL1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3208263-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | VentiRx Pharmaceuticals, Inc. (US) | 2017-08-23 | — | — | EP | disclosed |