Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.33 |
| ▸ | ACR | P10323 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19265705 | 0.93 | FDFT1 (0.38) | TLR8TLR7MAPTMEN1KMT2A | |
| SCHEMBL19265526 | 0.93 | TLR8 (0.40) | TLR8TLR7TARBP2MAPTMEN1 | |
| SCHEMBL19265638 | 0.93 | KDM4E (0.36) | TLR8TLR7GAACA9CA1 | |
| SCHEMBL19265644 | 0.91 | MMP2 (0.41) | TLR8TLR7ALDH1A1HPGDCASP1 | |
| SCHEMBL19265546 | 0.90 | TLR8 (0.33) | TLR8TLR7MAPTMEN1KMT2A | |
| SCHEMBL19265650 | 0.87 | KDM4E (0.39) | TLR8TLR7MAPTMEN1KMT2A | |
| SCHEMBL19265449 | 0.86 | TLR8 (0.41) | TLR8TLR7MEN1KMT2AALDH1A1 | |
| SCHEMBL19265647 | 0.85 | PRKCZ (0.37) | MEN1KMT2AALDH1A1 | |
| SCHEMBL19265550 | 0.84 | PKM (0.39) | MAPTKMT2APKMALDH1A1LMNA | |
| SCHEMBL19265503 | 0.84 | LRRK2 (0.36) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3208263-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | VentiRx Pharmaceuticals, Inc. (US) | 2017-08-23 | — | — | EP | disclosed |