Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | BCR | P11274 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19265449 | 0.91 | TLR8 (0.41) | HPGDTLR8MAPK1BRD4CREBBP | |
| SCHEMBL19265630 | 0.91 | TLR8 (0.36) | HPGDTLR8MAPK1BRD4CREBBP | |
| SCHEMBL19265534 | 0.90 | POLB (0.39) | HPGDTLR8MAPK1BRD4CREBBP | |
| SCHEMBL19265626 | 0.84 | HPGD (0.40) | HPGDTLR8MAPK1BRD4CREBBP | |
| SCHEMBL18771941 | 0.83 | HPGD (0.41) | HPGDTLR8MAPK1BRD4CREBBP | |
| SCHEMBL18771727 | 0.83 | TLR8 (0.42) | HPGDTLR8MAPK1KDM4EALDH1A1 | |
| SCHEMBL18771971 | 0.82 | HPGD (0.40) | HPGDTLR8MAPK1BRD4CREBBP | |
| SCHEMBL19265655 | 0.82 | HPGD (0.35) | HPGDTLR8KDM4EALDH1A1TSHR | |
| SCHEMBL19265459 | 0.80 | HPGD (0.40) | HPGDTLR8BRD4CREBBPALDH1A1 | |
| SCHEMBL19416476 | 0.79 | TLR8 (0.38) | HPGDTLR8MAPK1BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3208263-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | VentiRx Pharmaceuticals, Inc. (US) | 2017-08-23 | — | — | EP | disclosed |