SCHEMBL19483435

SCHEMBL19483435

CC(C)(C)N[C@@H](CCCCNC(=N)N)C(=O)C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 1/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ CYP1A2 P05177 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ NPY4R P50391 9/20 0.34
▸ NPY1R P25929 6/20 0.34
▸ NPY2R P49146 5/20 0.33
▸ NPY5R Q15761 5/20 0.33
▸ EPHX1 P07099 1/20 0.33
▸ SIRT6 Q8N6T7 1/20 0.33
▸ SIRT1 Q96EB6 1/20 0.33
▸ FOLH1 Q04609 1/20 0.32
▸ DPP7 Q9UHL4 1/20 0.31
▸ SIRT5 Q9NXA8 1/20 0.31
▸ GNAI3 P08754 1/20 0.31
▸ GNAO1 P09471 1/20 0.31
▸ GNAI1 P63096 1/20 0.31
▸ MAOA P21397 1/20 0.31
▸ MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19483434 1.00 ALOX15 (0.36) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL26880961 0.97 NPY4R (0.36) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL4572264 0.97 NPY4R (0.36) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL24591799 0.88 SIRT6 (0.35) MEN1KMT2AEPHX1SIRT6SIRT1
SCHEMBL21152809 0.84 C3AR1 (0.35) MEN1KMT2ASIRT6SIRT1FOLH1
SCHEMBL27113590 0.84 NPY4R (0.41) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL24917381 0.84 ALOX15 (0.36) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL14845337 0.83 NPY4R (0.38) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL23690778 0.83 MEN1 (0.40) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL22133108 0.83 ALOX15 (0.34) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230382950-A1 CYCLIC APELIN RECEPTOR AGONISTS HEPTARES THERAPEUTICS LIMITED (GB) 2023-11-30 — — US disclosed
US-20230382950-A1 CYCLIC APELIN RECEPTOR AGONISTS HEPTARES THERAPEUTICS LIMITED (GB) 2023-11-30 — — US disclosed
US-20230382949-A1 LINEAR APELIN RECEPTOR AGONISTS HEPTARES THERAPEUTICS LIMITED (GB) 2023-11-30 — — US disclosed
US-20230331770-A1 ARGININE MODIFICATION AND CONJUGATION METHODS Encodia, Inc. (US) 2023-10-19 — — US disclosed
US-20230331770-A1 ARGININE MODIFICATION AND CONJUGATION METHODS Encodia, Inc. (US) 2023-10-19 — — US disclosed
US-20170298097-A1 Peptide Derivatives and Uses Thereof NOSOPHARM (FR) 2017-10-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230382950-A1 CYCLIC APELIN RECEPTOR AGONISTS APLNR, MTNR1A, EDNRA ALOX15 1097/4885MEN1 2845/4885CYP1A2 2838/4885
US-20170298097-A1 Peptide Derivatives and Uses Thereof VIP, IAPP, NGLY1 ALOX15 4169/4885MEN1 215/4885CYP1A2 4882/4885
US-20230382949-A1 LINEAR APELIN RECEPTOR AGONISTS APLNR, MTNR1A, EDNRA ALOX15 680/4885MEN1 2874/4885CYP1A2 2600/4885
US-20230331770-A1 ARGININE MODIFICATION AND CONJUGATION METHODS ARGLU1, PRMT1, PRMT3 ALOX15 3648/4885MEN1 2978/4885CYP1A2 4825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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