SCHEMBL19267451

SCHEMBL19267451

Brc1cc2c(s1)sc1c3cc(-c4ccccc4)sc3sc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTP4A3 O75365 1/20 0.38
PTP4A2 Q12974 1/20 0.38
PTP4A1 Q93096 1/20 0.38
ALDH1A1 P00352 6/20 0.37
GAA P10253 3/20 0.37
HPGD P15428 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
RAB9A P51151 5/20 0.36
ADORA1 P30542 2/20 0.36
MAPT P10636 2/20 0.36
ADORA2A P29274 2/20 0.36
GFER P55789 1/20 0.36
PPARG P37231 1/20 0.36
NCOA2 Q15596 1/20 0.36
NCOA1 Q15788 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
CYP1A1 P04798 1/20 0.36
CYP1B1 Q16678 1/20 0.36
IKBKB O14920 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19301020 0.89 PTP4A3 (0.44) PTP4A3PTP4A2PTP4A1ALDH1A1GAA
SCHEMBL19267439 0.79 RAB9A (0.40) PTP4A3PTP4A2PTP4A1ALDH1A1GAA
SCHEMBL19267320 0.79
SCHEMBL19267450 0.78 PTP4A3 (0.37) PTP4A3PTP4A2PTP4A1ALDH1A1GAA
SCHEMBL19300821 0.76 ADORA2A (0.42) PTP4A3PTP4A2PTP4A1ALDH1A1HPGD
SCHEMBL19220747 0.75
SCHEMBL10054054 0.72 EGFR (0.36) PTP4A3PTP4A2PTP4A1ALDH1A1RAB9A
SCHEMBL19295432 0.71 ALDH1A1 (0.40) ALDH1A1HPGDMEN1KMT2ARAB9A
SCHEMBL2236236 0.71 CYP1A1 (0.55) PTP4A3PTP4A2PTP4A1ALDH1A1GAA
SCHEMBL19267447 0.71 ESR1 (0.42) ALDH1A1GAAHPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3208273-B1 ORGANIC SEMICONDUCTOR ELEMENT AND PRODUCTION METHOD FOR SAME, ORGANIC SEMICONDUCTOR COMPOSITION, ORGANIC SEMICONDUCTOR FILM, COMPOUND, AND OLIGOMER OR POLYMER FUJIFILM CORP (JP) 2019-07-10 EP disclosed
US-9954172-B2 Organic semiconductor element, manufacturing method thereof, organic semiconductor composition, organic semiconductor film, compound, and oligomer or polymer FUJIFILM CORPORATION (JP) 2018-04-24 US disclosed
US-20170250345-A1 ORGANIC SEMICONDUCTOR ELEMENT, MANUFACTURING METHOD THEREOF, ORGANIC SEMICONDUCTOR COMPOSITION, ORGANIC SEMICONDUCTOR FILM, COMPOUND, AND OLIGOMER OR POLYMER FUJIFILM CORPORATION (JP) 2017-08-31 US disclosed
US-20170250345-A1 ORGANIC SEMICONDUCTOR ELEMENT, MANUFACTURING METHOD THEREOF, ORGANIC SEMICONDUCTOR COMPOSITION, ORGANIC SEMICONDUCTOR FILM, COMPOUND, AND OLIGOMER OR POLYMER FUJIFILM CORPORATION (JP) 2017-08-31 US disclosed
EP-3208273-A1 ORGANIC SEMICONDUCTOR ELEMENT AND PRODUCTION METHOD FOR SAME, ORGANIC SEMICONDUCTOR COMPOSITION, ORGANIC SEMICONDUCTOR FILM, COMPOUND, AND OLIGOMER OR POLYMER Fujifilm Corporation (JP) 2017-08-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170250345-A1 ORGANIC SEMICONDUCTOR ELEMENT, MANUFACTURING METHOD THEREOF, ORGANIC SEMICONDUCTOR COMPOSITION, ORGANIC SEMICONDUCTOR FILM, COMPOUND, AND OLIGOMER OR POLYMER SLCO2A1, PROX1, POLQ PTP4A3 1811/4885PTP4A2 1608/4885PTP4A1 1671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.