Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | CHUK | O15111 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | TOP1 | P11387 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25435405 | 0.86 | AHR (0.50) | MAPTKIF11KDM4EALDH1A1HPGD | |
| SCHEMBL20129348 | 0.82 | MAPT (0.65) | ACHEMAPTKIF11KDM4EALDH1A1 | |
| SCHEMBL26055385 | 0.82 | HCRTR1 (0.48) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL18468267 | 0.79 | AHR (0.48) | MAPTKIF11KDM4EALDH1A1HPGD | |
| SCHEMBL23516781 | 0.79 | HCRTR1 (0.51) | MAPTKIF11KDM4EALDH1A1HPGD | |
| SCHEMBL16610292 | 0.77 | MAPT (0.63) | ACHEMAPTKIF11KDM4EALDH1A1 | |
| SCHEMBL17885351 | 0.77 | AHR (0.47) | MAPTKIF11KDM4EALDH1A1HPGD | |
| SCHEMBL24882841 | 0.77 | KDM4E (0.47) | MAPTKIF11KDM4EALDH1A1HCRTR1 | |
| SCHEMBL26045928 | 0.77 | KDM4E (0.47) | MAPTKIF11KDM4EALDH1A1HCRTR1 | |
| SCHEMBL15695203 | 0.76 | MMP12 (0.40) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200321533-A1 | COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE MATERIALS | THE SCRIPPS RESEARCH INSTITUTE | 2020-10-08 | — | — | US | disclosed |
| US-20180212158-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2018-07-26 | — | — | US | disclosed |
| US-20170244049-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200321533-A1 | COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE MATERIALS | ALDH1A2, DDT, CLTB | ACHE 914/4885MAPT 649/4885KIF11 2509/4885 |
| US-20180212158-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | MSN, DDT, NECTIN4 | ACHE 1237/4885MAPT 609/4885KIF11 3323/4885 |
| US-20170244049-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | CYBA, DDT, DRD1 | ACHE 1264/4885MAPT 640/4885KIF11 2340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.