Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31055714 | 0.92 | GAA (0.36) | GAAMEN1KMT2ATDP1 | |
| SCHEMBL31055698 | 0.91 | NLRP3 (0.45) | NLRP3GAA | |
| SCHEMBL26975465 | 0.88 | MEN1 (0.48) | MEN1KMT2ATDP1 | |
| SCHEMBL26975354 | 0.87 | NLRP3 (0.42) | NLRP3GAA | |
| SCHEMBL26975378 | 0.82 | GAA (0.56) | NLRP3GAAMEN1KMT2ATDP1 | |
| SCHEMBL26975356 | 0.81 | MEN1 (0.43) | NLRP3MEN1KMT2A | |
| SCHEMBL26975352 | 0.81 | NLRP3 (0.43) | NLRP3GAA | |
| SCHEMBL26975350 | 0.80 | NLRP3 (0.44) | NLRP3GAA | |
| SCHEMBL26975363 | 0.80 | ACHE (0.44) | NLRP3GAA | |
| SCHEMBL26975375 | 0.79 | NLRP3 (0.43) | NLRP3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017140778-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | THE UNIVERSITY OF QUEENSLAND (AU) | 2017-08-24 | — | — | WO | disclosed |