SCHEMBL26975465

SCHEMBL26975465

CC(C)c1cccc(C(C)C)c1NC(=O)NS(=O)(=O)N1CCN(CC(F)(F)F)CC1

nearest known ligand 0.69

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.48
▸ KMT2A Q03164 1/20 0.48
▸ TDP1 Q9NUW8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31055714 0.88 GAA (0.36) MEN1KMT2ATDP1
SCHEMBL19272291 0.88 NLRP3 (0.39) MEN1KMT2ATDP1
SCHEMBL31055698 0.87 NLRP3 (0.45) —
SCHEMBL26975355 0.86 MEN1 (0.52) MEN1KMT2ATDP1
SCHEMBL20636166 0.83 MEN1 (0.46) MEN1KMT2ATDP1
SCHEMBL26975357 0.83 — —
SCHEMBL7572034 0.82 MEN1 (0.58) MEN1KMT2ATDP1
SCHEMBL7567422 0.81 MEN1 (0.56) MEN1KMT2ATDP1
SCHEMBL26975353 0.81 NLRP3 (0.51) —
SCHEMBL22433298 0.80 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3416948-B1 INDACENE BEARING SULFONYLUREAS AS ANTI-INFLAMMATORY AGENTS UNIV QUEENSLAND (AU) 2024-07-24 — — EP claimed
US-11858922-B2 Sulfonylureas and related compounds and use of same THE UNIVERSITY OF QUEENSLAND (AU) 2024-01-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11858922-B2 Sulfonylureas and related compounds and use of same NLRP3, NOD1, PYCARD MEN1 2219/4885KMT2A 3753/4885TDP1 2296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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