SCHEMBL1927673

SCHEMBL1927673

O=C1[CH]c2ccccc2C=C1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.46
LMNA P02545 3/20 0.46
ALDH1A1 P00352 2/20 0.46
BCHE P06276 2/20 0.46
POLB P06746 2/20 0.46
ACHE P22303 2/20 0.46
RECQL P46063 2/20 0.46
HSD17B10 Q99714 2/20 0.46
IDO1 P14902 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
KDM4E B2RXH2 1/20 0.46
PTPRC P08575 1/20 0.46
THRB P10828 1/20 0.46
PKM P14618 1/20 0.46
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
PTPN1 P18031 1/20 0.46
CES1 P23141 1/20 0.46
PTPN22 Q9Y2R2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29418986 0.74 MAPT (0.53) MAPTLMNAALDH1A1BCHEPOLB
SCHEMBL29375766 0.74 MAPT (0.53) MAPTLMNAALDH1A1BCHEPOLB
SCHEMBL33554 0.74
SCHEMBL3767165 0.74 MAPT (0.53) MAPTLMNAALDH1A1BCHEPOLB
SCHEMBL29398195 0.74
1,2-Naphthoquinone SCHEMBL7746067 0.74 PTPRC (0.87) MAPTLMNAALDH1A1BCHEPOLB
SCHEMBL29120205 0.72 MAPT (0.45) MAPTLMNAALDH1A1BCHEPOLB
SCHEMBL29120222 0.72 MAPT (0.45) MAPTLMNAALDH1A1BCHEPOLB
Water SCHEMBL10406928 0.71
SCHEMBL8984812 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10851187-B2 Bridged metallocene catalysts with a pendant group 13 element, catalyst systems containing same, processes for making a polymer product using same, and products made from same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-12-01 US claimed
EP-2219073-B1 Holographic media and photopolymer compositions COVESTRO DEUTSCHLAND AG (DE) 2020-06-03 EP claimed
US-20190284312-A1 Mixed Catalyst Systems Containing Bridged Metallocenes with a Pendant Group 13 Element, Processes for Making a Polymer Product Using Same, and Products Made from Same EXXONMOBIL CHEMICAL PATENTS INC. 2019-09-19 US claimed
WO-2019152209-A1 BRIDGED METALLOCENE CATALYSTS WITH A PENDANT GROUP 13 ELEMENT, CATALYST SYSTEMS CONTAINING SAME, PROCESSES FOR MAKING A POLYMER PRODUCT USING SAME, AND PRODUCTS MADE FROM SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-08-08 WO claimed
WO-2019152210-A1 MIXED CATALYST SYSTEMS CONTAINING BRIDGED METALLOCENES WITH A PENDANT GROUP 13 ELEMENT, PROCESSES FOR MAKING A POLYMER PRODUCT USING SAME, AND PRODUCTS MADE FROM SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-08-08 WO claimed
US-20190233552-A1 Bridged Metallocene Catalysts with a Pendant Group 13 Element, Catalyst Systems Containing Same, Processes for Making a Polymer Product Using Same, and Products Made from Same EXXONMOBIL CHEMICAL PATENTS INC. 2019-08-01 US claimed
EP-2219075-B1 Glycidyl ether acrylate urethanes as writing monomers COVESTRO DEUTSCHLAND AG (DE) 2017-06-28 EP claimed
US-8329773-B2 Holographic media and photopolymers BAYER MATERIALSCIENCE AG (DE) 2012-12-11 US claimed
US-20110065827-A1 NOVEL HOLOGRAPHIC MEDIA AND PHOTOPOLYMERS BAYER MATERIALSCIENCE AG (DE) 2011-03-17 US claimed
EP-2219073-A1 New holographic media and photopolymers Bayer MaterialScience AG (DE) 2010-08-18 EP claimed
EP-2219075-A1 New holographic media and photopolymers Bayer MaterialScience AG (DE) 2010-08-18 EP claimed
US-6013360-A MONOMERS DERIVED FROM AROMATIC TETRACARBOXYLIC ACID DIANHYDRIDES; BUBBLE-BLOWN; FOOD PACKAGING, PHOTOGRAPHIC FILMS SINCO ENGINEERING, S.P.A. (IT) 2000-01-11 US claimed
WO-1999065881-A1 HETEROCYCLIC COMPOUNDS AS HYPOGLYCEMIC AGENTS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1999-12-23 WO claimed
WO-1996026207-A1 THIAZOLIDINE AND OXAZOLIDINE INDOLES WITH HYPOCLYCEMIC ACTIVITY NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1996-08-29 WO claimed
WO-1996011196-A1 PYRAZOLYLMETHYL-THIAZOLIDINES USEFUL AS HYPOGLYCEMIC AGENTS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1996-04-18 WO claimed
US-5191124-A Photoinitiators for Cationic Polymerization BASF AKTIENGESELLSCHAFT (DE) 1993-03-02 US claimed
WO-2024109798-A1 LIPID COMPOUND AND LIPID NANOPARTICLE COMPOSITION 苏州艾博生物科技有限公司 2024-05-30 WO disclosed
WO-2024083171-A1 LIPID COMPOUND AND LIPID NANOPARTICLE COMPOSITION 苏州艾博生物科技有限公司 2024-04-25 WO disclosed
US-4364991-A RESIN WITH A PHOSPHORYLATED AMIDE MCDONNELL DOUGLAS CORPORATION (US) 1982-12-21 US disclosed
US-4076537-A Light-sensitive materials containing organo tellurium or selenium compounds and sensitizers FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110065827-A1 NOVEL HOLOGRAPHIC MEDIA AND PHOTOPOLYMERS ALOX5, PTGIS, ALOX5AP MAPT 982/4885LMNA 2377/4885ALDH1A1 2498/4885
US-10851187-B2 Bridged metallocene catalysts with a pendant group 13 element, catalyst systems containing same, processes for making a polymer product using same, and products made from same COPE, PFAS, MCM4 MAPT 3022/4885LMNA 3928/4885ALDH1A1 2955/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.