Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12229140 | 0.80 | ALOX5 (0.42) | ALOX5ADRA1DGSK3BGAANPC1 | |
| SCHEMBL19277642 | 0.79 | ADRA1D (0.31) | ADRA1D | |
| SCHEMBL2608970 | 0.74 | ALOX5 (0.47) | ALOX5ADRA1DGSK3BNPC1RAB9A | |
| SCHEMBL4460 | 0.73 | UTS2R (0.42) | ALOX5ADRA1DGSK3B | |
| SCHEMBL827163 | 0.72 | — | — | |
| SCHEMBL7228966 | 0.72 | CYP3A4 (0.42) | ALOX5ADRA1DNPC1RAB9AALDH1A1 | |
| SCHEMBL6569286 | 0.71 | ALOX5 (0.49) | ALOX5ADRA1DGSK3BNPC1RAB9A | |
| SCHEMBL14544792 | 0.69 | ALOX5 (0.43) | ALOX5ADRA1DGSK3BNPC1RAB9A | |
| SCHEMBL25445382 | 0.69 | — | — | |
| SCHEMBL19122447 | 0.69 | ALOX5 (0.46) | ALOX5ADRA1DGSK3BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017140274-A1 | TRICYCLIC COMPOUND SERVING AS IMMUNOMODULATOR | 正大天晴药业集团股份有限公司 | 2017-08-24 | — | — | WO | disclosed |