SCHEMBL192797

SCHEMBL192797

CC1=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc2C1[Zr](Cl)(Cl)(C1C(C)=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc21)[SiH](C)C1CCCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5607814 0.91
SCHEMBL273374 0.86 BRD4 (0.31)
SCHEMBL4465300 0.85 PTGS2 (0.30)
SCHEMBL4470232 0.84
SCHEMBL5584095 0.83 PTGS2 (0.31)
SCHEMBL272367 0.82 NR1H4 (0.31)
SCHEMBL4479305 0.82 CYP3A4 (0.34)
SCHEMBL4481383 0.82 CYP3A4 (0.34)
SCHEMBL5608292 0.82
SCHEMBL5548482 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2746336-B1 Polypropylene blend for pressure pipes BOREALIS AG (AT) 2017-04-12 EP claimed
EP-2562215-B1 POLYPROPYLENE BLEND FOR PIPES BOREALIS AG (AT) 2016-03-30 EP claimed
WO-2014095946-A1 POLYPROPYLENE BLEND FOR PRESSURE PIPES BOREALIS AG (AT) 2014-06-26 WO claimed
WO-2013029699-A1 POLYPROPYLENE BLEND FOR PIPES BOREALIS AG (AT) 2013-03-07 WO claimed
EP-2562215-A1 Polypropylene blend for pipes Borealis AG (AT) 2013-02-27 EP claimed
US-20240209127-A1 NEW METALLOCENE CATALYST AND USE THEREOF TOTALENERGIES ONETECH BELGIUM (BE) 2024-06-27 US disclosed
EP-4347667-A1 NEW METALLOCENE CATALYST AND USE THEREOF TotalEnergies OneTech Belgium (BE) 2024-04-10 EP disclosed
US-20240002555-A1 IN-SITU REACTOR BLEND OF ZIEGLER-NATTA CATALYSED, NUCLEATED POLYPROPYLENE AND A METALLOCENE CATALYSED POLYPROPYLENE BOREALIS AG (AT) 2024-01-04 US disclosed
EP-4247864-A1 IN-SITU REACTOR BLEND OF ZIEGLER-NATTA CATALYSED, NUCLEATED POLYPROPYLENE AND A METALLOCENE CATALYSED POLYPROPYLENE Borealis AG (AT) 2023-09-27 EP disclosed
WO-2023099528-A1 DUAL CATALYST COMPOSITIONS TOTALENERGIES ONETECH BELGIUM (BE) 2023-06-08 WO disclosed
WO-2023099529-A1 POLYMERIZATION PROCESS USING DUAL CATALYST COMPOSITIONS TOTALENERGIES ONETECH BELGIUM (BE) 2023-06-08 WO disclosed
US-11352376-B2 Catalysts BOREALIS AG (AT) 2022-06-07 US disclosed
US-7232869-B2 Catalyst composition for olefin polymerization NOVOLEN TECHNOLOGY HOLDINGS, C.V. (NL) 2007-06-19 US disclosed
US-20070082806-A1 Metallocene catalysts, their synthesis and their use for the polymerization of olefins PACZKOWSKI NICOLA S 2007-04-12 US disclosed
US-7169864-B2 Loeading and heating a catalyst support with an alumoxane and further loading with a Group IVB metallocene and a second aluminoxane cocatalyst alone or in combination with a Lewis Acid or ionic compound; improved catalyst selectivity and polymerization efficiency NOVOLEN TECHNOLOGY HOLDINGS, C.V. (NL) 2007-01-30 US disclosed
WO-2006124231-A1 CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2006-11-23 WO disclosed
US-20060264587-A1 Catalyst composition for olefin polymerization NOVOLEN TECHNOLOGY HOLDINGS, C.V. (NL) 2006-11-23 US disclosed
WO-2006060544-A1 METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2006-06-08 WO disclosed
US-20060116490-A1 Metallocene catalysts, their synthesis and their use for the polymerization of olefins LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2006-06-01 US disclosed
US-20050239979-A1 Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2005-10-27 US disclosed