Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4470232 | 0.99 | — | — | |
| SCHEMBL5584095 | 0.97 | PTGS2 (0.31) | PTGS2 | |
| SCHEMBL4479305 | 0.96 | CYP3A4 (0.34) | — | |
| SCHEMBL4481383 | 0.96 | CYP3A4 (0.34) | — | |
| SCHEMBL4466342 | 0.94 | — | — | |
| SCHEMBL4473491 | 0.94 | — | — | |
| SCHEMBL4464228 | 0.94 | — | — | |
| SCHEMBL4463629 | 0.94 | — | — | |
| SCHEMBL4191804 | 0.94 | — | — | |
| SCHEMBL4457475 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569651-B2 | Transition metal compound, ligand system, catalyst system and its use for the polymerization and copolymerization of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2009-08-04 | — | — | US | disclosed |
| US-7342078-B2 | Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins | BASELL POLYOLEFINE GMBH (DE) | 2008-03-11 | — | — | US | disclosed |
| EP-1392710-B1 | REDUCTION OF THE CONCENTRATION OF INORGANIC BY-PRODUCTS AND ORGANOMETALLIC BY-PRODUCTS IN THE PREPARATION OF METALLOCENES AND ECONOMICAL RECOVERY OF THE STARTING MATERIALS USED | BASELL POLYOLEFINE GMBH (DE) | 2007-11-28 | — | — | EP | disclosed |
| US-7223878-B2 | Reduction of concentration of inorganic by-products and organometallic by-products in the preparation of metallocenes and economical recovery of the starting materials used | BASELL POLYOLEFINE GMBH (DE) | 2007-05-29 | — | — | US | disclosed |
| US-20060020096-A1 | Transition metal compound, ligand system, catalyst system and its use for the polymerization and copolymerization of olefins | SCHOTTEK JORG | 2006-01-26 | — | — | US | disclosed |
| US-20040176624-A1 | Reduction of concentration of inorganic by-products and organometallic by-products in the preparation of metallocenes and economical recovery of the starting materials used | EQUISTAR CHEMICALS, LP | 2004-09-09 | — | — | US | disclosed |
| US-20030149199-A1 | Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2003-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176624-A1 | Reduction of concentration of inorganic by-products and organometallic by-products in the preparation of metallocenes and economical recovery of the starting materials used | AS3MT, DNMT1, OSGEP | PTGS2 2446/4885 |
| US-20030149199-A1 | Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins | PORCN, PGR, PPOX | PTGS2 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.