Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18714924 | 0.79 | HPGD (0.47) | ALDH1A1MAPTRAB9A | |
| SCHEMBL15255288 | 0.77 | HRH3 (0.44) | MAPT | |
| SCHEMBL20837819 | 0.77 | SRC (0.32) | MAPTRAB9A | |
| SCHEMBL31527813 | 0.77 | UCHL1 (0.47) | ALDH1A1MAPTRAB9A | |
| SCHEMBL23002471 | 0.76 | THRA (0.40) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL20775111 | 0.76 | HRH3 (0.42) | MAPT | |
| SCHEMBL28379715 | 0.75 | ALDH1A1 (0.38) | TRPA1ALDH1A1TSHRMAPT | |
| SCHEMBL15706583 | 0.74 | TAAR1 (0.50) | ALDH1A1TSHR | |
| SCHEMBL28712370 | 0.74 | PLK1 (0.44) | ALDH1A1 | |
| SCHEMBL28815558 | 0.74 | HRH3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4350056-A2 | GENETIC ENCODING OF CHEMICAL POST-TRANSLATIONAL MODIFICATION FOR PHAGE-DISPLAYED LIBRARIES | The Governors Of The University Of Alberta (CA) | 2024-04-10 | — | — | EP | disclosed |
| EP-3209819-B1 | GENETIC ENCODING OF CHEMICAL POST-TRANSLATIONAL MODIFICATION FOR PHAGE-DISPLAYED LIBRARIES | UNIV ALBERTA (CA) | 2024-02-14 | — | — | EP | disclosed |
| CN-110872299-B | P-benzoquinone-bis-triazole core skeleton derivative and preparation method and application thereof | 广州中医药大学(广州中医药研究院) | 2022-09-30 | — | — | CN | disclosed |
| US-10724034-B2 | Genetic encoding of chemical post-translational modification for phage-displayed libraries | 48Hour Discovery Inc. (CA) | 2020-07-28 | — | — | US | disclosed |
| CN-110872299-A | P-benzoquinone-bis-triazole core skeleton derivative and preparation method and application thereof | 广州中医药大学(广州中医药研究院) | 2020-03-10 | — | — | CN | disclosed |
| US-20170355982-A1 | GENETIC ENCODING OF CHEMICAL POST-TRANSLATIONAL MODIFICATION FOR PHAGE-DISPLAYED LIBRARIES | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2017-12-14 | — | — | US | disclosed |
| EP-3209819-A1 | GENETIC ENCODING OF CHEMICAL POST-TRANSLATIONAL MODIFICATION FOR PHAGE-DISPLAYED LIBRARIES | The Governors Of The University Of Alberta (CA) | 2017-08-30 | — | — | EP | disclosed |