SCHEMBL1928068

SCHEMBL1928068

C[SiH](C)O[Si](O[SiH](C)C)(O[SiH](C)C)O[SiH](C)C.C[SiH](C)O[Si](O[SiH](C)C)(O[SiH](C)C)c1ccccc1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL94175 0.93 ESR1 (0.33) ESR1ESR2
SCHEMBL20493844 0.91 ESR1 (0.32) ESR1ESR2
SCHEMBL94083 0.84 ESR1 (0.31) ESR1ESR2
SCHEMBL15630780 0.83 POLB (0.33) ESR1ESR2
SCHEMBL5701660 0.83 POLB (0.33) ESR1ESR2
SCHEMBL3438614 0.79 ESR1 (0.32) ESR1ESR2
SCHEMBL94043 0.79 ESR1 (0.32) ESR1ESR2
SCHEMBL18416013 0.79
SCHEMBL15453122 0.78
SCHEMBL5701575 0.78 LTA4H (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2328953-A1 SILICON CONTAINING POLYMERIC MATERIALS Advanced Medical Optics, Inc. (US) 2011-06-08 EP disclosed
WO-2010027519-A1 SILICON CONTAINING POLYMERIC MATERIALS ADVANCED MEDICAL OPTICS (US) 2010-03-11 WO disclosed