Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.65 |
| ▸ | MAOB | P27338 | 2/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | KIF11 | P52732 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16742068 | 1.00 | TGM2 (0.65) | TGM2MAOBEPHX2MAPTCA12 | |
| SCHEMBL13113128 | 0.85 | TGM2 (0.63) | TGM2MAOBEPHX2MAPTCA12 | |
| SCHEMBL29246314 | 0.84 | TRPV1 (0.60) | EPHX2MAPTTRPV1KIF11NPC1 | |
| SCHEMBL13174972 | 0.83 | ALDH1A1 (0.68) | TGM2MAOBEPHX2MAPTALDH1A1 | |
| SCHEMBL13174657 | 0.81 | ALDH1A1 (0.68) | TGM2MAOBEPHX2MAPTCA12 | |
| SCHEMBL13100947 | 0.81 | TGM2 (0.58) | TGM2MAOBEPHX2MAPTCA12 | |
| SCHEMBL21090683 | 0.81 | TGM2 (0.53) | TGM2MAOBEPHX2ALDH1A1TRPV1 | |
| SCHEMBL29246294 | 0.80 | TGM2 (0.61) | TGM2MAOBMAPTCA12CA1 | |
| SCHEMBL27767027 | 0.80 | TGM2 (0.71) | TGM2MAOBEPHX2CA12CA1 | |
| SCHEMBL9943583 | 0.80 | TGM2 (0.56) | TGM2MAOBEPHX2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209770-A1 | NOVEL SELECTION MARKER FOR CELL TRANSFECTION AND PROTEIN PRODUCTION | SANOFI (FR) | 2017-08-30 | — | — | EP | disclosed |