Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.53 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.53 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.53 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.53 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.53 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.53 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.53 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.53 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.53 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.53 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.53 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.53 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.53 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4535391 | 0.83 | TGM2 (0.54) | TGM2MEN1KMT2AMAOBPSMB11 | |
| SCHEMBL16742068 | 0.80 | TGM2 (0.65) | TGM2MEN1KMT2AMAOBEPHX2 | |
| SCHEMBL8907266 | 0.80 | PSMB11 (0.56) | TGM2MEN1KMT2AMAOBPSMB11 | |
| SCHEMBL19280682 | 0.80 | TGM2 (0.65) | TGM2MEN1KMT2AMAOBEPHX2 | |
| SCHEMBL13174972 | 0.80 | ALDH1A1 (0.68) | TGM2MEN1KMT2AMAOBEPHX2 | |
| SCHEMBL13113128 | 0.78 | TGM2 (0.63) | TGM2MEN1KMT2AMAOBEPHX2 | |
| SCHEMBL15707930 | 0.78 | TGM2 (0.55) | TGM2MEN1KMT2AMAOBEPHX2 | |
| SCHEMBL15707928 | 0.78 | TGM2 (0.55) | TGM2MEN1KMT2AMAOBEPHX2 | |
| SCHEMBL9943778 | 0.78 | CNR1 (0.80) | TGM2MEN1KMT2APSMB11PSMA7 | |
| SCHEMBL13174657 | 0.75 | ALDH1A1 (0.68) | TGM2MAOBEPHX2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464368-A1 | CATHEPSIN C INHIBITORS | Glaxo Group Limited (GB) | 2012-06-20 | — | — | EP | disclosed |