SCHEMBL19280729

SCHEMBL19280729

N#Cc1ccc(Oc2ccccc2O)cc1C#N

nearest known ligand 0.69

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
AR P10275 13/20 0.69
CYP19A1 P11511 1/20 0.49
MAOB P27338 1/20 0.47
ALDH1A1 P00352 2/20 0.47
HPGD P15428 2/20 0.47
POLB P06746 1/20 0.46
GAA P10253 1/20 0.46
NPSR1 Q6W5P4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1940627 0.88 AR (0.57) ARCYP19A1MAOBALDH1A1HPGD
SCHEMBL19280732 0.84 AR (0.52) ARCYP19A1MAOBALDH1A1HPGD
SCHEMBL6013913 0.83 AR (0.57) ARCYP19A1MAOBALDH1A1HPGD
SCHEMBL9746114 0.83 ALDH1A1 (0.56) ARCYP19A1MAOBALDH1A1HPGD
SCHEMBL4166581 0.82 AR (1.00) AR
SCHEMBL8632247 0.81 ALDH1A1 (0.54) ARCYP19A1MAOBALDH1A1HPGD
SCHEMBL7115607 0.80 GAA (0.57) ARCYP19A1MAOBALDH1A1HPGD
SCHEMBL15268658 0.80 AR (0.75) ARCYP19A1MAOBALDH1A1HPGD
SCHEMBL13327517 0.80 AR (0.53) ARCYP19A1MAOBALDH1A1HPGD
SCHEMBL20964552 0.79 AR (0.56) ARCYP19A1MAOBALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106939080-B Nitrile-based resin mixture and preparation method thereof 中国人民解放军国防科学技术大学 2020-01-03 CN claimed
EP-3521340-A1 A PHTHALONITRILE MONOMER MODIFIED BY ORGANOPHOSPHATE FRAGMENTS, A METHOD FOR OBTAINING SAME, A BINDER BASED THEREON, AND A PREPREG Joint Stock Company Scientific and Production Association "Unichimtek" (JSC PSA "Unichimtek) (RU) 2019-08-07 EP claimed
US-20190218235-A1 Phthalonitrile Monomer Modified with Organophosphorus Fragments, a Method of Producing thereof, a Binder Based Thereon, and a Prepreg JOINT STOCK COMPANY SCIENTIFIC AND PRODUCTION ASSOCIATION "UNICHIMTEK" (JSC PSA "UNICHIMTEK") (RU) 2019-07-18 US claimed
CN-106939080-B Nitrile-based resin mixture and preparation method thereof 中国人民解放军国防科学技术大学 2020-01-03 CN disclosed
EP-3521340-A1 A PHTHALONITRILE MONOMER MODIFIED BY ORGANOPHOSPHATE FRAGMENTS, A METHOD FOR OBTAINING SAME, A BINDER BASED THEREON, AND A PREPREG Joint Stock Company Scientific and Production Association "Unichimtek" (JSC PSA "Unichimtek) (RU) 2019-08-07 EP disclosed
US-20190218235-A1 Phthalonitrile Monomer Modified with Organophosphorus Fragments, a Method of Producing thereof, a Binder Based Thereon, and a Prepreg JOINT STOCK COMPANY SCIENTIFIC AND PRODUCTION ASSOCIATION "UNICHIMTEK" (JSC PSA "UNICHIMTEK") (RU) 2019-07-18 US disclosed
EP-3211023-A1 PHTHALONITRILE MONOMER MODIFIED WITH ORGANOSILICON FRAGMENTS Joint Stock Company Scientific and Production Association "Unichimtek" (JSC PSA "Unichimtek) (RU) 2017-08-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190218235-A1 Phthalonitrile Monomer Modified with Organophosphorus Fragments, a Method of Producing thereof, a Binder Based Thereon, and a Prepreg THEM6, NOTUM, PNN AR 2119/4885CYP19A1 1229/4885MAOB 1907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.