Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.57 |
| ▸ | AR | P10275 | 12/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR4 | O00206 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1940627 | 0.88 | AR (0.57) | GAAARALDH1A1CYP19A1MAOB | |
| SCHEMBL6013913 | 0.83 | AR (0.57) | GAAARALDH1A1CYP19A1MAOB | |
| SCHEMBL9746114 | 0.83 | ALDH1A1 (0.56) | GAAARALDH1A1CYP19A1MAOB | |
| SCHEMBL20230387 | 0.82 | ALDH1A1 (0.46) | ARALDH1A1CYP19A1MAOBHPGD | |
| SCHEMBL23795081 | 0.81 | AR (0.51) | ARALDH1A1CYP19A1MAOBHPGD | |
| SCHEMBL8632247 | 0.81 | ALDH1A1 (0.54) | GAAARALDH1A1CYP19A1MAOB | |
| SCHEMBL19280729 | 0.80 | AR (0.69) | GAAARALDH1A1CYP19A1MAOB | |
| SCHEMBL15268658 | 0.80 | AR (0.75) | GAAARALDH1A1CYP19A1MAOB | |
| SCHEMBL20964552 | 0.79 | AR (0.56) | GAAARALDH1A1CYP19A1MAOB | |
| SCHEMBL23795062 | 0.78 | AR (0.55) | ARCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116741965-A | Phthalonitrile resin modified silicon-carbon negative electrode coating material and preparation method thereof | 中钢集团鞍山热能研究院有限公司 | 2023-09-12 | — | — | CN | claimed |
| CN-109096488-B | Phthalonitrile resin composition and preparation method thereof | 中国人民解放军国防科学技术大学 | 2021-02-26 | — | — | CN | claimed |
| CN-109096753-B | Nitrile resin composite material and preparation method thereof | 中国人民解放军国防科学技术大学 | 2021-02-23 | — | — | CN | claimed |
| CN-116741965-A | Phthalonitrile resin modified silicon-carbon negative electrode coating material and preparation method thereof | 中钢集团鞍山热能研究院有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-113939557-B | Curable fluoropolymer compositions comprising phthalonitrile and nucleophilic functional group containing compounds and cured articles made therefrom | 3M创新有限公司 | 2023-08-18 | — | — | CN | disclosed |
| US-11492457-B2 | Curable fluoropolymer compositions comprising a compound containing a phthalonitrile and a nucleophilic functional group and cured articles therefrom | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2022-11-08 | — | — | US | disclosed |
| US-20220204723-A1 | CURABLE FLUOROPOLYMER COMPOSITIONS COMPRISING A COMPOUND CONTAINING A PHTHALONITRILE AND A NUCLEOPHILIC FUNCTIONAL GROUP AND CURED ARTICLES THEREFROM | 3M INNOVATIVE PROPERTIES COMPANY | 2022-06-30 | — | — | US | disclosed |
| US-20220204723-A1 | CURABLE FLUOROPOLYMER COMPOSITIONS COMPRISING A COMPOUND CONTAINING A PHTHALONITRILE AND A NUCLEOPHILIC FUNCTIONAL GROUP AND CURED ARTICLES THEREFROM | 3M INNOVATIVE PROPERTIES COMPANY | 2022-06-30 | — | — | US | disclosed |
| EP-3980488-A1 | CURABLE FLUOROPOLYMER COMPOSITIONS COMPRISING A COMPOUND CONTAINING A PHTHALONITRILE AND A NUCLEOPHILIC FUNCTIONAL GROUP AND CURED ARTICLES THEREFROM | 3M Innovative Properties Company (US) | 2022-04-13 | — | — | EP | disclosed |
| CN-113939557-A | Curable fluoropolymer compositions comprising phthalonitrile-containing and nucleophilic functional group-containing compounds and cured articles made therefrom | 3M创新有限公司 | 2022-01-14 | — | — | CN | disclosed |
| CN-109096488-B | Phthalonitrile resin composition and preparation method thereof | 中国人民解放军国防科学技术大学 | 2021-02-26 | — | — | CN | disclosed |
| CN-109096753-B | Nitrile resin composite material and preparation method thereof | 中国人民解放军国防科学技术大学 | 2021-02-23 | — | — | CN | disclosed |
| WO-2020245683-A1 | CURABLE FLUOROPOLYMER COMPOSITIONS COMPRISING A COMPOUND CONTAINING A PHTHALONITRILE AND A NUCLEOPHILIC FUNCTIONAL GROUP AND CURED ARTICLES THEREFROM | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2020-12-10 | — | — | WO | disclosed |
| CN-106939080-B | Nitrile-based resin mixture and preparation method thereof | 中国人民解放军国防科学技术大学 | 2020-01-03 | — | — | CN | disclosed |
| US-20030186944-A1 | Such as 4-(2-(3-dimethylaminobenzoylamino)phenoxy)phthalic acid for treatment/prevention of diabetes; for inhibiting liver glycogen phosphorylase; dietetics | KRISTIANSEN MARIT (DK) | 2003-10-02 | — | — | US | disclosed |
| US-6590118-B1 | Used in treatment of and/or prevention of diabetes, especially non-insulin dependent diabetes (Type 2 diabetes) | NOVO NORDISK A/S (DK) | 2003-07-08 | — | — | US | disclosed |
| EP-1220832-A1 | NOVEL AROMATIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2002-07-10 | — | — | EP | disclosed |
| WO-2001023347-A1 | NOVEL AROMATIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2001-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186944-A1 | Such as 4-(2-(3-dimethylaminobenzoylamino)phenoxy)phthalic acid for treatment/prevention of diabetes; for inhibiting liver glycogen phosphorylase; dietetics | PYGL, GYS2, PYGM | GAA 99/4885RCE1 2133/4885AR 3826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.