Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.40 |
| ▸ | FABP7 | O15540 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19517972 | 0.84 | KMT2A (0.45) | KMT2AEPHX2FABP5FABP7CASP3 | |
| SCHEMBL17935568 | 0.84 | CASP3 (0.45) | KMT2AEPHX2FABP5FABP7PTPN1 | |
| SCHEMBL30430376 | 0.84 | KMT2A (0.43) | KMT2AEPHX2FABP5FABP7CASP3 | |
| SCHEMBL19280973 | 0.82 | KMT2A (0.45) | KMT2AEPHX2FABP5FABP7CASP3 | |
| SCHEMBL9234192 | 0.80 | KMT2A (0.43) | KMT2AEPHX2FABP5FABP7CASP3 | |
| SCHEMBL30341743 | 0.79 | KMT2A (0.49) | KMT2AEPHX2FABP5FABP7CASP3 | |
| SCHEMBL31120791 | 0.79 | PTPN1 (0.48) | KMT2AEPHX2PTPN1CASP3MDM4 | |
| SCHEMBL15119354 | 0.78 | KMT2A (0.60) | KMT2AEPHX2FABP5FABP7CASP3 | |
| SCHEMBL15058849 | 0.78 | KMT2A (0.55) | KMT2AEPHX2FABP5FABP7CASP3 | |
| SCHEMBL9449368 | 0.77 | PTPN1 (0.51) | KMT2AEPHX2PTPN1CASP3MDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325314-A1 | N-Methyl Scanning Mutagenesis | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2009-12-31 | — | — | US | disclosed |