Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17442972 | 0.90 | PNMT (0.33) | PNMTALDH1A1TSHRATMNPSR1 | |
| SCHEMBL1930284 | 0.86 | PNMT (0.43) | PNMTALDH1A1TSHRATMNPSR1 | |
| SCHEMBL27854621 | 0.84 | PNMT (0.42) | PNMTALDH1A1TSHRATMNPSR1 | |
| SCHEMBL27836596 | 0.84 | PNMT (0.42) | PNMTALDH1A1TSHRATMNPSR1 | |
| SCHEMBL28794932 | 0.84 | PNMT (0.42) | PNMTALDH1A1TSHRATMNPSR1 | |
| SCHEMBL27836591 | 0.81 | PNMT (0.44) | PNMTALDH1A1TSHRATMNPSR1 | |
| SCHEMBL8760303 | 0.75 | PNMT (0.46) | PNMTALDH1A1TSHRATMNPSR1 | |
| SCHEMBL20542552 | 0.74 | PGR (0.36) | PNMTALDH1A1TSHRATMNPSR1 | |
| Fluorene SCHEMBL25291666 | 0.73 | MAOA (0.50) | PNMTALDH1A1TSHRATMNPSR1 | |
| SCHEMBL4563163 | 0.72 | KMT2A (0.47) | ALDH1A1TSHRCYP3A4HSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034296-A | Photoconductive imaging members with fluorene polyester hole transporting layers | XEROX CORPORATION (US) | 1991-07-23 | — | — | US | claimed |
| US-7956350-B2 | Crosslinkable substituted fluorene compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-06-07 | — | — | US | disclosed |
| US-20070063191-A1 | Crosslinkable substituted fluorene compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-03-22 | — | — | US | disclosed |
| WO-2005049548-A1 | CROSSLINKABLE SUBSTITUTED FLUORENE COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-06-02 | — | — | WO | disclosed |
| US-5223361-A | Improved bonding strength between layers | XEROX CORPORATION (US) | 1993-06-29 | — | — | US | disclosed |
| US-5034296-A | Photoconductive imaging members with fluorene polyester hole transporting layers | XEROX CORPORATION (US) | 1991-07-23 | — | — | US | disclosed |
| US-4983482-A | Photoconductive imaging members with polyurethane hole transporting layers | XEROX CORPORATION (US) | 1991-01-08 | — | — | US | disclosed |
| US-4853308-A | Photoresponsive imaging members with fluorene hole transporting layers | XEROX CORPORATION (US) | 1989-08-01 | — | — | US | disclosed |
| US-4853308-A | Photoresponsive imaging members with fluorene hole transporting layers | XEROX CORPORATION (US) | 1989-08-01 | — | — | US | disclosed |