Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1930285 | 0.82 | GPR3 (0.53) | SLC22A2SLC22A3GPR3BCHEACHE | |
| SCHEMBL17442971 | 0.82 | SLC22A2 (0.37) | SLC22A2SLC22A3GPR3BCHEACHE | |
| SCHEMBL28058725 | 0.78 | BCHE (0.39) | SLC22A2SLC22A3GPR3BCHEACHE | |
| SCHEMBL28167099 | 0.77 | GPR3 (0.55) | SLC22A2SLC22A3GPR3BCHEACHE | |
| SCHEMBL5182601 | 0.74 | KCNH2 (0.49) | CRHR1ALDH1A1TP53KCNH2 | |
| SCHEMBL9278064 | 0.72 | KCNH2 (0.44) | ALDH1A1TP53KCNH2 | |
| SCHEMBL9798892 | 0.70 | KCNH2 (0.47) | ALDH1A1TP53KCNH2 | |
| SCHEMBL28289612 | 0.69 | GPR3 (0.44) | SLC22A2SLC22A3GPR3BCHEACHE | |
| SCHEMBL18507942 | 0.69 | CRHR1 (0.43) | CRHR1ALDH1A1TP53KCNH2 | |
| SCHEMBL18498551 | 0.68 | CRHR1 (0.44) | CRHR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034296-A | Photoconductive imaging members with fluorene polyester hole transporting layers | XEROX CORPORATION (US) | 1991-07-23 | — | — | US | claimed |
| US-7956350-B2 | Crosslinkable substituted fluorene compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-06-07 | — | — | US | disclosed |
| US-20070063191-A1 | Crosslinkable substituted fluorene compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-03-22 | — | — | US | disclosed |
| WO-2005049548-A1 | CROSSLINKABLE SUBSTITUTED FLUORENE COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-06-02 | — | — | WO | disclosed |
| US-5223361-A | Improved bonding strength between layers | XEROX CORPORATION (US) | 1993-06-29 | — | — | US | disclosed |
| US-5034296-A | Photoconductive imaging members with fluorene polyester hole transporting layers | XEROX CORPORATION (US) | 1991-07-23 | — | — | US | disclosed |
| US-4983482-A | Photoconductive imaging members with polyurethane hole transporting layers | XEROX CORPORATION (US) | 1991-01-08 | — | — | US | disclosed |
| US-4853308-A | Photoresponsive imaging members with fluorene hole transporting layers | XEROX CORPORATION (US) | 1989-08-01 | — | — | US | disclosed |
| US-4853308-A | Photoresponsive imaging members with fluorene hole transporting layers | XEROX CORPORATION (US) | 1989-08-01 | — | — | US | disclosed |