SCHEMBL1930285

SCHEMBL1930285

CCCCCN(CCCCC)C1c2ccccc2-c2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.53
SLC22A2 O15244 1/20 0.51
SLC22A3 O75751 1/20 0.51
ACHE P22303 2/20 0.47
BCHE P06276 1/20 0.47
HTR2A P28223 2/20 0.39
KCNH2 Q12809 2/20 0.38
CHRM2 P08172 1/20 0.37
HTR1A P08908 1/20 0.37
ADRA2A P08913 1/20 0.37
CHRM1 P11229 1/20 0.37
DRD1 P21728 1/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
ADRA1A P35348 1/20 0.37
OPRM1 P35372 1/20 0.37
DRD3 P35462 1/20 0.37
SLC6A3 Q01959 1/20 0.37
HRH3 Q9Y5N1 1/20 0.37
HRH1 P35367 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28167099 0.94 GPR3 (0.55) GPR3SLC22A2SLC22A3ACHEBCHE
SCHEMBL1928348 0.82 SLC22A2 (0.40) GPR3SLC22A2SLC22A3ACHEBCHE
SCHEMBL28289612 0.81 GPR3 (0.44) GPR3SLC22A2SLC22A3ACHEBCHE
SCHEMBL10885181 0.81 KMT2A (0.49) HTR2AHRH1
SCHEMBL17442971 0.78 SLC22A2 (0.37) GPR3SLC22A2SLC22A3ACHEBCHE
SCHEMBL24885669 0.75 GPR3 (0.54) GPR3SLC22A2SLC22A3HTR2A
SCHEMBL28287654 0.73 BCHE (0.40) SLC22A2SLC22A3ACHEBCHE
SCHEMBL877438 0.72 HTR2A (0.56) ACHEBCHEHTR2A
SCHEMBL14962124 0.72 SLC22A2 (0.63) GPR3SLC22A2SLC22A3ACHEBCHE
Hydrochloric Acid SCHEMBL29351559 0.71 GPR3 (0.46) GPR3SLC22A2SLC22A3ACHEBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10113065-B1 Two-photon absorbing compounds and methods of making same GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2018-10-30 US claimed
US-7652136-B2 Diarylaminofluorene-based organometallic phosphors and organic light-emitting devices made with such compounds THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2010-01-26 US claimed
US-20080091021-A1 Diarylaminofluorene-based organometallic phosphors and organic light-emitting devices made with such compounds HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY, THE (CN) 2008-04-17 US claimed
US-10113065-B1 Two-photon absorbing compounds and methods of making same GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2018-10-30 US disclosed
US-10113065-B1 Two-photon absorbing compounds and methods of making same GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2018-10-30 US disclosed
US-9859499-B2 Polymer comprising an unsymmetric diarylaminofluorene unit SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2018-01-02 US disclosed
US-7956350-B2 Crosslinkable substituted fluorene compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-07 US disclosed
US-7652136-B2 Diarylaminofluorene-based organometallic phosphors and organic light-emitting devices made with such compounds THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2010-01-26 US disclosed
US-7652136-B2 Diarylaminofluorene-based organometallic phosphors and organic light-emitting devices made with such compounds THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2010-01-26 US disclosed
US-20080091021-A1 Diarylaminofluorene-based organometallic phosphors and organic light-emitting devices made with such compounds HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY, THE (CN) 2008-04-17 US disclosed
US-20080091021-A1 Diarylaminofluorene-based organometallic phosphors and organic light-emitting devices made with such compounds HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY, THE (CN) 2008-04-17 US disclosed
US-20070063191-A1 Crosslinkable substituted fluorene compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-22 US disclosed
WO-2005049548-A1 CROSSLINKABLE SUBSTITUTED FLUORENE COMPOUNDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-06-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080091021-A1 Diarylaminofluorene-based organometallic phosphors and organic light-emitting devices made with such compounds ORC3, MCM3, TEC GPR3 195/4885SLC22A2 3943/4885SLC22A3 3154/4885
US-10113065-B1 Two-photon absorbing compounds and methods of making same TBXA2R, TBXAS1, TPD52L2 GPR3 893/4885SLC22A2 2089/4885SLC22A3 3034/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.