Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | STS | P08842 | 2/20 | 0.50 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8285387 | 0.89 | MAPT (0.57) | MEN1KMT2ASTSUSP30MAPT | |
| SCHEMBL7893585 | 0.88 | NAMPT (0.51) | MEN1KMT2AUSP30MAPTPTPN2 | |
| SCHEMBL19284243 | 0.88 | ALDH1A1 (0.58) | KMT2ASTSMAPTPTPN2PTPN1 | |
| SCHEMBL19284221 | 0.87 | MAPT (0.67) | MAPTPTPN2PTPN1PTPN6SETD7 | |
| SCHEMBL3599783 | 0.86 | MEN1 (0.47) | MEN1KMT2ASTSUSP30MAPT | |
| SCHEMBL19284238 | 0.85 | MAPT (0.55) | MEN1KMT2AMAPTPTPN2PTPN1 | |
| SCHEMBL8285767 | 0.84 | MAPT (0.57) | MEN1KMT2ASTSUSP30MAPT | |
| SCHEMBL19284228 | 0.84 | MAPT (0.53) | MEN1KMT2AMAPT | |
| SCHEMBL19284222 | 0.84 | P2RX7 (0.66) | MEN1KMT2ASTSMAPTNAMPT | |
| SCHEMBL20236629 | 0.83 | MEN1 (0.68) | MEN1KMT2ASTSMAPTPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190308956-A1 | PIPERAZINE DERIVATIVES AS ANTIVIRAL AGENTS WITH INCREASED THERAPEUTIC ACTIVITY | SERVICIO ANDALUZ DE SALUD (ES) | 2019-10-10 | — | — | US | disclosed |
| EP-3419626-A1 | PIPERAZINE DERIVATIVES AS ANTIVIRAL AGENTS WITH INCREASED THERAPEUTIC ACTIVITY | Servicio Andaluz De Salud (ES) | 2019-01-02 | — | — | EP | disclosed |
| WO-2017144624-A1 | PIPERAZINE DERIVATIVES AS ANTIVIRAL AGENTS WITH INCREASED THERAPEUTIC ACTIVITY | SERVICIO ANDALUZ DE SALUD (ES) | 2017-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190308956-A1 | PIPERAZINE DERIVATIVES AS ANTIVIRAL AGENTS WITH INCREASED THERAPEUTIC ACTIVITY | ZC3HAV1, EIF2AK2, MAVS | MEN1 4861/4885KMT2A 2257/4885STS 4767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.