SCHEMBL1928668

SCHEMBL1928668

C=CCC1(CC=C)c2ccc(Cl)cc2-c2cc(Cl)ccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.44
PDK2 Q15119 2/20 0.38
HPGD P15428 3/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C19 P33261 1/20 0.36
CES1 P23141 2/20 0.35
TGM2 P21980 2/20 0.35
GAA P10253 1/20 0.35
TSHR P16473 1/20 0.35
PPOX P50336 1/20 0.34
S100A4 P26447 1/20 0.33
POLB P06746 1/20 0.33
NPC1 O15118 1/20 0.31
TP53 P04637 1/20 0.31
ALOX15 P16050 1/20 0.31
NFKB1 P19838 1/20 0.31
RAB9A P51151 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1928893 0.85 PDK2 (0.43) PGRPDK2HPGDCYP1A2CYP3A4
SCHEMBL1927827 0.77 PDK2 (0.39) PGRPDK2
SCHEMBL1926884 0.77 TGM2 (0.35) PGRHPGDCES1TGM2TSHR
SCHEMBL1926840 0.77 TGM2 (0.35) PGRCES1TGM2
SCHEMBL6019476 0.76 PDK2 (0.37) PGRPDK2HPGDCYP1A2CYP3A4
SCHEMBL30777632 0.74 PDK2 (0.44) PDK2HPGDCYP3A4CES1TGM2
SCHEMBL29187718 0.74 PDK2 (0.44) PDK2HPGDCYP3A4CES1TGM2
SCHEMBL1929820 0.73 CYP1A2 (0.39) PGRHPGDCYP1A2CYP2C19GAA
SCHEMBL30511096 0.71 PGR (0.49) PGRPDK2CYP1A2CYP3A4CYP2C19
SCHEMBL88451 0.71 PGR (0.49) PGRPDK2CYP1A2CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7964691-B2 5,5-diallyl-2,2-dimethyl-1,3-dioxane as monomer units; polymerization catalysts; heat resistance SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-21 US disclosed
US-7956145-B2 Polymerization of 1,6-heptadiene in the presence of a catalyst formed by contacting a transition metal with a diimino aluminum or boron compound, giving a polymer structure of alternating ethylene and cyclopentene; superior balance between a heat resistance and workability SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-07 US disclosed
WO-2009038031-A1 BLOCK COPOLYMER AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-26 WO disclosed
WO-2009038006-A1 RANDOM COPOLYMER AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-26 WO disclosed
US-20080234450-A1 DIENE POLYMER AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-25 US disclosed
US-20080214755-A1 OLEFIN-DIENE COPOLYMER AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-04 US disclosed