Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | THRB | P10828 | 11/20 | 0.53 |
| ▸ | THRA | P10827 | 9/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29062390 | 0.90 | THRA (0.59) | L3MBTL1THRBTHRAPLK1KMT2A | |
| SCHEMBL19043219 | 0.86 | ALDH1A1 (0.52) | L3MBTL1THRBTHRAPLK1KMT2A | |
| SCHEMBL30089521 | 0.85 | L3MBTL1 (0.85) | L3MBTL1THRBTHRAPLK1KMT2A | |
| SCHEMBL4265689 | 0.82 | L3MBTL1 (1.00) | L3MBTL1THRBTHRAPLK1KMT2A | |
| SCHEMBL2562463 | 0.82 | L3MBTL1 (0.64) | L3MBTL1THRBTHRAPLK1KMT2A | |
| SCHEMBL8122707 | 0.80 | L3MBTL1 (0.71) | L3MBTL1THRBTHRAPLK1HSD17B3 | |
| SCHEMBL29062362 | 0.80 | L3MBTL1 (0.45) | L3MBTL1THRBTHRAPLK1ALDH1A1 | |
| SCHEMBL6937309 | 0.79 | L3MBTL1 (0.69) | L3MBTL1THRBTHRAPLK1KMT2A | |
| SCHEMBL14115647 | 0.79 | L3MBTL1 (0.50) | L3MBTL1THRBTHRAPLK1KMT2A | |
| SCHEMBL2118360 | 0.78 | KMT2A (0.66) | L3MBTL1THRBKMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403459-B | Preparation method of 1, 4-dicarbonyl compound | 广州自远生物科技有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-115403459-A | Preparation method of 1, 4-dicarbonyl compound | 广州自远生物科技有限公司 | 2022-11-29 | — | — | CN | disclosed |
| US-20180093981-A1 | 2-Acylaminopropoanol-Type Glucosylceramide Synthase Inhibitors | GENZYME CORPORATION | 2018-04-05 | — | — | US | disclosed |
| US-9745294-B2 | 2-acylaminopropoanol-type glucosylceramide synthase inhibitors | GENZYME CORPORATION (US) | 2017-08-29 | — | — | US | disclosed |
| US-9744153-B2 | 2-acylaminopropoanol-type glucosylceramide synthase inhibitors | GENZYME CORPORATION (US) | 2017-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180093981-A1 | 2-Acylaminopropoanol-Type Glucosylceramide Synthase Inhibitors | ASAH2, GBA1, GAA | L3MBTL1 3762/4885THRB 1715/4885THRA 2056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.