Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23151968 | 0.92 | ESR1 (0.54) | LMNASMN1; SMN2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9650301 | 0.80 | LMNA (0.72) | LMNASMN1; SMN2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL5185777 | 0.80 | LMNA (0.72) | LMNASMN1; SMN2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9647625 | 0.80 | LMNA (0.72) | LMNASMN1; SMN2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1934741 | 0.80 | LMNA (0.72) | LMNASMN1; SMN2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8943247 | 0.80 | LMNA (0.72) | LMNASMN1; SMN2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11315675 | 0.80 | LMNA (0.72) | LMNASMN1; SMN2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9744746 | 0.80 | LMNA (0.72) | LMNASMN1; SMN2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9737668 | 0.80 | LMNA (0.72) | LMNASMN1; SMN2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL5482347 | 0.80 | LMNA (0.72) | LMNASMN1; SMN2CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838975-B1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2017-08-30 | — | — | EP | disclosed |