Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 6/20 | 0.36 |
| ▸ | IGF1R | P08069 | 6/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 6/20 | 0.36 |
| ▸ | POLQ | O75417 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11916220 | 0.71 | INSR (0.52) | INSRIGF1RALK | |
| SCHEMBL19313005 | 0.69 | ALK (0.43) | INSRIGF1RALKPOLQ | |
| SCHEMBL19288797 | 0.69 | NPC1 (0.38) | — | |
| SCHEMBL1491772 | 0.64 | ALDH1A1 (0.53) | INSRIGF1RALK | |
| Hydrochloric Acid SCHEMBL11900704 | 0.62 | ALDH1A1 (0.53) | INSRIGF1RALK | |
| SCHEMBL12018596 | 0.62 | TAS1R3 (0.39) | INSRIGF1RALKPOLQ | |
| SCHEMBL18338693 | 0.62 | INSR (0.37) | INSRIGF1RALKPOLQ | |
| SCHEMBL9685872 | 0.61 | NPC1 (0.39) | — | |
| SCHEMBL25033630 | 0.60 | MAOB (0.53) | — | |
| SCHEMBL1491622 | 0.60 | ALDH1A1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3210609-A1 | PHOSPHOROUS DERIVATIVES AS KINASE INHIBITORS | ARIAD PHARMACEUTICALS, INC. (US) | 2017-08-30 | — | — | EP | disclosed |