SCHEMBL1928882

SCHEMBL1928882

CN1c2ccccc2N(c2ccccc2)C1I

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PDGFRB P09619 1/20 0.34
▸ PTPN2 P17706 1/20 0.34
▸ PTPN1 P18031 1/20 0.34
▸ GAA P10253 3/20 0.34
▸ POLB P06746 1/20 0.34
▸ MEN1 O00255 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ LMNA P02545 2/20 0.33
▸ GPR3 P46089 1/20 0.32
▸ GSK3A P49840 1/20 0.32
▸ GSK3B P49841 1/20 0.32
▸ ALDH1A1 P00352 2/20 0.31
▸ PAX8 Q06710 1/20 0.31
▸ MCL1 Q07820 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1926229 0.85 HSD11B1 (0.35) PDGFRBPTPN2PTPN1LMNAHTT
SCHEMBL28841479 0.80 PDGFRB (0.42) PDGFRBPTPN2PTPN1GAAMEN1
SCHEMBL28954321 0.79 MEN1 (0.42) GAAPOLBMEN1CYP2C19KMT2A
SCHEMBL24398363 0.78 GAA (0.44) PDGFRBPTPN2PTPN1GAAPOLB
SCHEMBL16711487 0.78 GAA (0.44) PDGFRBPTPN2PTPN1GAAPOLB
SCHEMBL11941264 0.78 GAA (0.44) PDGFRBPTPN2PTPN1GAAPOLB
SCHEMBL22147810 0.72 KDM4E (0.38) PDGFRBPTPN2PTPN1GAAMEN1
SCHEMBL13456559 0.72 POLB (0.32) PDGFRBPTPN2PTPN1GAAPOLB
SCHEMBL29843820 0.72 HDAC4 (0.37) GAAPOLBSMN1; SMN2NPSR1GSK3A
SCHEMBL12787319 0.72 GAA (0.39) GAAPOLBMEN1CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115160374-A Stable OLED materials and devices with improved stability 通用显示公司 2022-10-11 — — CN disclosed
US-7956192-B2 Carbene containing metal complexes as OLEDs THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2011-06-07 — — US disclosed
US-20090302754-A1 CARBENE CONTAINING METAL COMPLEXES AS OLEDS TSAI JUI-YI 2009-12-10 — — US disclosed
US-7598388-B2 Can stabily emit light with various spectra, including high energy blue spectra; tris(1-(2'-(9',9'-dimethyl)fluorenyl)-3-methyl-imidazolin-2-ylidene-C,C3') iridium(III); organic light emitting devices; combining L, a carbene ligand precursor, with an organic solvent at about 175 degrees C. THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2009-10-06 — — US disclosed
WO-2005113704-A2 LUMINESCENT COMPOUNDS WITH CARBENE LIGANDS THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2005-12-01 — — WO disclosed
US-20050258742-A1 Carbene containing metal complexes as OLEDs UNIVERSAL DISPLAY CORPORATION 2005-11-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090302754-A1 CARBENE CONTAINING METAL COMPLEXES AS OLEDS OPRD1, OGFRL1, OCIAD1 PDGFRB 1611/4885PTPN2 4821/4885PTPN1 4838/4885
US-20050258742-A1 Carbene containing metal complexes as OLEDs OPRD1, OGFRL1, OCIAD1 PDGFRB 1611/4885PTPN2 4821/4885PTPN1 4838/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback