SCHEMBL16711487

SCHEMBL16711487

C[C@H]1N(C)c2ccccc2N1c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 4/20 0.44
▸ ALDH1A1 P00352 2/20 0.44
▸ KDM4E B2RXH2 2/20 0.44
▸ HPGD P15428 1/20 0.44
▸ ALOX12 P18054 1/20 0.44
▸ PTPN2 P17706 1/20 0.39
▸ PTPN1 P18031 1/20 0.39
▸ GPR3 P46089 1/20 0.37
▸ PDGFRB P09619 1/20 0.35
▸ POLB P06746 1/20 0.35
▸ LMNA P02545 2/20 0.33
▸ GSK3A P49840 1/20 0.33
▸ GSK3B P49841 1/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.32
▸ PAX8 Q06710 1/20 0.32
▸ MCL1 Q07820 1/20 0.32
▸ HTT P42858 1/20 0.32
▸ MAOA P21397 1/20 0.32
▸ G6PD P11413 1/20 0.32
▸ BRD4 O60885 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24398363 1.00 GAA (0.44) GAAALDH1A1KDM4EHPGDALOX12
SCHEMBL11941264 1.00 GAA (0.44) GAAALDH1A1KDM4EHPGDALOX12
SCHEMBL12787319 0.87 GAA (0.39) GAAALDH1A1KDM4EHPGDALOX12
SCHEMBL16709175 0.86 GAA (0.37) GAAALDH1A1KDM4EHPGDALOX12
SCHEMBL16709176 0.84 KDM4E (0.36) GAAALDH1A1KDM4EHPGDALOX12
SCHEMBL16711467 0.80 GAA (0.33) GAAALDH1A1KDM4EHPGDALOX12
SCHEMBL30353863 0.79 GAA (0.62) GAAALDH1A1KDM4EHPGDALOX12
SCHEMBL1049325 0.79 GAA (0.62) GAAALDH1A1KDM4EHPGDALOX12
SCHEMBL17952498 0.78 TDP2 (0.38) G6PDHTR2BSIGMAR1
SCHEMBL12349380 0.78 ALDH1A1 (0.42) GAAALDH1A1KDM4EHPGDALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 — — US disclosed
US-20230331756-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed
US-20230303601-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 — — US disclosed
US-20230263048-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-08-17 — — US disclosed
US-11697653-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-11 — — US disclosed
US-9502672-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-11-22 — — US disclosed
US-9306179-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-04-05 — — US disclosed
US-20150129840-A1 OSMIUM COMPLEXES COMPRISING THREE DIFFERENT BIDENTATE LIGANDS AND METHOD OF MAKING THE SAME UNIVERSAL DISPLAY CORPORATION (US) 2015-05-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303601-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MGLL, SELENOI, APOL1 GAA 3830/4885ALDH1A1 1729/4885KDM4E 3250/4885
US-11697653-B2 Organic electroluminescent materials and devices L1CAM, SOD1, EPCAM GAA 969/4885ALDH1A1 380/4885KDM4E 4003/4885
US-20230263048-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 GAA 1957/4885ALDH1A1 36/4885KDM4E 3349/4885
US-20230331756-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, SSB, LBR GAA 3876/4885ALDH1A1 1702/4885KDM4E 4219/4885
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRD1, L1CAM, OPRM1 GAA 3702/4885ALDH1A1 2748/4885KDM4E 4161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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