SCHEMBL19289697

SCHEMBL19289697

Cc1ccnc(N(c2cccc3ccccc23)c2cc(C)c3ccc4c(N(c5ccccn5)c5cccc6ccccc56)cc(C)c5ccc2c3c54)c1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
NPC1 O15118 1/20 0.34
POLB P06746 1/20 0.34
RAB9A P51151 1/20 0.34
CCR1 P32246 1/20 0.32
CCR8 P51685 1/20 0.32
CYP2A6 P11509 3/20 0.32
CYP1A2 P05177 2/20 0.32
TRPM8 Q7Z2W7 1/20 0.31
DHFR P00374 1/20 0.31
MAOA P21397 1/20 0.31
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12368299 0.93 CCR1 (0.36) KMT2ANPC1POLBCCR1CCR8
SCHEMBL22386526 0.90 CCR1 (0.34) NPC1POLBCCR1CCR8CYP2A6
SCHEMBL24353134 0.89 ALDH1A1 (0.34) CCR1CCR8CYP2A6CYP1A2DHFR
SCHEMBL26166680 0.89 L3MBTL1 (0.37) KMT2ANPC1POLBRAB9ACCR1
SCHEMBL17657216 0.88 SIGMAR1 (0.36) CCR1CCR8CYP2A6DHFRSIGMAR1
SCHEMBL24470273 0.88 SIGMAR1 (0.36) CCR1CCR8CYP2A6DHFRSIGMAR1
SCHEMBL17343515 0.88 SIGMAR1 (0.36) CCR1CCR8CYP2A6DHFRSIGMAR1
SCHEMBL13321033 0.86 KDM4E (0.36) KMT2ANPC1POLBCYP2A6CYP1A2
SCHEMBL24860186 0.85 SIGMAR1 (0.36) CCR1CCR8CYP2A6DHFRSIGMAR1
SCHEMBL19623061 0.85 CCR1 (0.33) CCR1CCR8CYP2A6SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3211681-A1 ORGANIC LIGHT-EMITTING APPARATUS Samsung Electronics Co., Ltd. (KR) 2017-08-30 EP disclosed