SCHEMBL1929137

SCHEMBL1929137

[CH2]COCCOCCOC(=O)c1cccc(NC(=O)NS(=O)(=O)c2ccc(C)cc2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
SMN1; SMN2 Q16637 3/20 0.51
TCF4 P15884 1/20 0.50
CTNNB1 P35222 1/20 0.50
TP53 P04637 2/20 0.48
KMT2A Q03164 4/20 0.47
MEN1 O00255 2/20 0.47
CA12 O43570 2/20 0.45
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
CA9 Q16790 2/20 0.45
CA4 P22748 1/20 0.45
CA6 P23280 1/20 0.45
CA5A P35218 1/20 0.45
CA7 P43166 1/20 0.45
CA13 Q8N1Q1 1/20 0.45
CA14 Q9ULX7 1/20 0.45
RAB9A P51151 3/20 0.45
NPC1 O15118 2/20 0.45
NPSR1 Q6W5P4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1930666 0.91 FBP1 (0.53) SMN1; SMN2CA12CA1CA2CA9
SCHEMBL6324534 0.91 LMNA (0.57) LMNASMN1; SMN2TCF4CTNNB1TP53
SCHEMBL6329326 0.89 LMNA (0.51) LMNASMN1; SMN2TCF4CTNNB1TP53
SCHEMBL6324679 0.89 LMNA (0.51) LMNASMN1; SMN2TCF4CTNNB1TP53
SCHEMBL6731502 0.88 CA2 (0.54) LMNATP53KMT2AMEN1CA12
SCHEMBL1929599 0.88 LMNA (0.58) LMNASMN1; SMN2TCF4CTNNB1TP53
SCHEMBL1929671 0.88 LMNA (0.58) LMNASMN1; SMN2TCF4CTNNB1TP53
SCHEMBL6323613 0.88 LMNA (0.49) LMNASMN1; SMN2TCF4CTNNB1TP53
SCHEMBL1929143 0.87 LMNA (0.57) LMNASMN1; SMN2TCF4CTNNB1TP53
SCHEMBL1928221 0.87 LMNA (0.57) LMNASMN1; SMN2TCF4CTNNB1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7956007-B2 support and a heat-sensitive recording layer, the heat-sensitive recording layer comprising a colorless or pale-colored basic dye and a developer, the developer being 4-allyloxy-4'-hydroxydiphenylsulfone and the heat-sensitive recording layer further comprising a compound represented by formula (I): OJI PAPER CO., LTD. (JP) 2011-06-07 US disclosed
EP-1842688-B1 HEAT-SENSITIVE RECORDING MATERIAL OJI PAPER CO (JP) 2009-10-07 EP disclosed
US-20080167184-A1 Heat-Sensitive Recording Material OJI PAPER CO., LTD. (JP) 2008-07-10 US disclosed
US-7312177-B2 Thermosensitive recording materials OJI PAPER CO., LTD. (JP) 2007-12-25 US disclosed
EP-1512545-B1 Thermosensitive recording materials OJI PAPER CO (JP) 2007-11-07 EP disclosed
EP-1842688-A1 HEAT-SENSITIVE RECORDING MATERIAL Oji Paper Co., Ltd. (JP) 2007-10-10 EP disclosed
US-20050054528-A1 Thermosensitive recording materials OJI PAPER CO., LTD. (JP) 2005-03-10 US disclosed
EP-1512545-A1 Thermosensitive recording materials Oji Paper Co., Ltd. (JP) 2005-03-09 EP disclosed