Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | TLR4 | O00206 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25820645 | 0.89 | CHRNB4 (0.46) | CHRNB4CHRNA3CARM1PRMT6TLR4 | |
| SCHEMBL4568821 | 0.86 | CHRNA3 (0.51) | CHRNB4CHRNA3TLR4TLR2CHRNB2 | |
| SCHEMBL2208539 | 0.84 | CHRNB4 (0.48) | CHRNB4CHRNA3TLR4TLR2SIRT2 | |
| SCHEMBL13881607 | 0.84 | CHRNB4 (0.46) | CHRNB4CHRNA3TLR4TLR2SIRT2 | |
| SCHEMBL2206912 | 0.84 | CHRNB4 (0.56) | CHRNB4CHRNA3TLR4TLR2SIRT2 | |
| SCHEMBL4568824 | 0.84 | CHRNB4 (0.47) | CHRNB4CHRNA3TLR4TLR2PARP15 | |
| SCHEMBL2204534 | 0.81 | TLR4 (0.45) | CHRNB4CHRNA3TLR4TLR2SIRT2 | |
| SCHEMBL3963497 | 0.81 | TLR4 (0.47) | CHRNB4CHRNA3TLR4TLR2SIRT2 | |
| SCHEMBL19291642 | 0.78 | HTR1B (0.50) | CARM1PRMT6TLR4TLR2SIRT2 | |
| SCHEMBL25819210 | 0.78 | HTR1B (0.50) | CARM1PRMT6TLR4TLR2SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3210966-A1 | ALKOXYPHENYLPROPYLAMINES FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION | Acucela, Inc. (US) | 2017-08-30 | — | — | EP | disclosed |